MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients

Effect of Long and Short Radiotherapy on MMP-7 Levels in Rectal Cancer Treatment

To analyse the effects of radiation therapy on inflammation and matrilysin levels in rectal cancer patients.

Inclusion Criteria:

Adenocarcinoma of the rectum, ability to understand written and oral information, written consent.

Exclusion Criteria:

Colon cancer, benign tumors, impaired general condition of patient, declining to participate in the study, synchronous colonic tumors, logistical reasons, inability to understand written and/or oral information, previous pelvic irradiation, ongoing immunosuppressive therapy, diabetes with systemic complications.