Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Hospital Universitario Virgen Macarena | OTHER |
Not provided
Not provided
Not provided
Not provided
Bacteremia
The Hypothesis of the study are the followings:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Epidemiology and prognostic factors of bacteremia episodes. |
| From day 0 to day 30 |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical management of patients with bacteremia during the episode. |
| From day 0 to day 30 |
| Differences in the management between types of services, wards and hospitals. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
It will be included all episodes of bacteremia diagnosed over a year in all participating hospitals in patients over 13 years old. It´s no possible to make a calculation of the sample size, this will depend on the type of hospital, the number of beds of the same and the number of blood cultures that are requested during the period of recruitment of the study.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jesús RodrÃguez-Baño, MD PhD | Unidad ClÃnica de Enfermedades Infecciosas, MicrobiologÃa. Hospital Universitario Virgen Macarena | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Public Health Agency Business Hospital de Poniente. | El Ejido | AlmerÃa | 04700 | Spain | ||
| General Hospital of Granollers |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 14668610 | Result | Garnacho-Montero J, Garcia-Garmendia JL, Barrero-Almodovar A, Jimenez-Jimenez FJ, Perez-Paredes C, Ortiz-Leyba C. Impact of adequate empirical antibiotic therapy on the outcome of patients admitted to the intensive care unit with sepsis. Crit Care Med. 2003 Dec;31(12):2742-51. doi: 10.1097/01.CCM.0000098031.24329.10. | |
| 16424713 | Result |
| Label | URL |
|---|---|
| European Surveillance of Antimicrobial Consumption Network (ESAC-Net). | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Microbial strains
Comparison between different services and hospital wards of variables regarding on the management of episodes. |
| From day 0 to day 30 |
| Influence of clinical management in the prognosis. | - Identifying prognostic factors related with mortality, clinical failure and recurrence. | From day 0 to day 30 |
| Developing and validating a predictive model for early and late mortality. | - Developing and validating a predictive model for mortality based in prognostic factors related with mortality. | From day 0 to day 30 |
| Quality indicators in the management of bacteremia. | - Identifying quality indicators in the management of episodes of bacteremia. | From day 0 to day 30 |
| Interventions made by Bacteremia Team. |
| From day 0 to day 30 |
| Granollers |
| Barcelona |
| 08402 |
| Spain |
| University Hospital Mútua de Terrasa | Terrassa | Barcelona | 08221 | Spain |
| Hospital Punta Europa | Algeciras | Cádiz | 11207 | Spain |
| Jerez de la Frontera Hospital | Jerez de la Frontera | Cádiz | 11138 | Spain |
| Hospital San Juan de la Cruz | Úbeda | Jaen | 23400 | Spain |
| Hospital El Bierzo | Ponferrada | León | 24404 | Spain |
| Costa del Sol Hospital | Márbella | Málaga | 29603 | Spain |
| University Hospital of Vigo | Vigo | Pontevedra | 36204 | Spain |
| University General Hospital of Alicante | Alicante | 03012 | Spain |
| Torrecárdenas Hospital | AlmerÃa | 04009 | Spain |
| L´ Esperit Sant ( Santa Coloma Granemet) Hospital | Barcelona | 08923 | Spain |
| University Hospital of Burgos | Burgos | 09006 | Spain |
| University Hospital Puerta del Mar | Cadiz | 11009 | Spain |
| La Linea de la Concepción Hospital | Cadiz | 11300 | Spain |
| Puerto Real Hospital | Cadiz | 11510 | Spain |
| University Hospital Reina SofÃa | Córdoba | 14004 | Spain |
| University Hospital San Cecilio | Granada | 18012 | Spain |
| University Hospital Virgen de las Nieves | Granada | 18014 | Spain |
| Ciudad de Jaén Hospital | Jaén | 23007 | Spain |
| University Hospital of León | León | 24001 | Spain |
| University Hospital Arnau de Vilanova | Lleida | 25198 | Spain |
| University Hospital Carlos Haya ( Málaga) | Málaga | 29010 | Spain |
| Central University Hospital of Asturias | Oviedo | 33011 | Spain |
| University Clinic of Navarra | Pamplona | 31008 | Spain |
| University Hospital Marqués de Valdecilla | Santander | 30008 | Spain |
| University Hospital Virgen Macarena | Seville | 41009 | Spain |
| University Virgen de Valme Hospital | Seville | 41014 | Spain |
| Universitary Hospital Cruces | Vizcaya | 48903 | Spain |
| Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, Moreno R, Carlet J, Le Gall JR, Payen D; Sepsis Occurrence in Acutely Ill Patients Investigators. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006 Feb;34(2):344-53. doi: 10.1097/01.ccm.0000194725.48928.3a. |
| 19845694 | Result | Rodriguez-Bano J, Lopez-Prieto MD, Portillo MM, Retamar P, Natera C, Nuno E, Herrero M, del Arco A, Munoz A, Tellez F, Torres-Tortosa M, Martin-Aspas A, Arroyo A, Ruiz A, Moya R, Corzo JE, Leon L, Perez-Lopez JA; SAEI/SAMPAC Bacteraemia Group. Epidemiology and clinical features of community-acquired, healthcare-associated and nosocomial bloodstream infections in tertiary-care and community hospitals. Clin Microbiol Infect. 2010 Sep;16(9):1408-13. doi: 10.1111/j.1469-0691.2009.03089.x. |
| 23929889 | Result | Lopez-Cortes LE, Del Toro MD, Galvez-Acebal J, Bereciartua-Bastarrica E, Farinas MC, Sanz-Franco M, Natera C, Corzo JE, Lomas JM, Pasquau J, Del Arco A, Martinez MP, Romero A, Muniain MA, de Cueto M, Pascual A, Rodriguez-Bano J; REIPI/SAB group. Impact of an evidence-based bundle intervention in the quality-of-care management and outcome of Staphylococcus aureus bacteremia. Clin Infect Dis. 2013 Nov;57(9):1225-33. doi: 10.1093/cid/cit499. Epub 2013 Aug 8. |
| 19191635 | Result | Pappas PG, Kauffman CA, Andes D, Benjamin DK Jr, Calandra TF, Edwards JE Jr, Filler SG, Fisher JF, Kullberg BJ, Ostrosky-Zeichner L, Reboli AC, Rex JH, Walsh TJ, Sobel JD; Infectious Diseases Society of America. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009 Mar 1;48(5):503-35. doi: 10.1086/596757. |
| 22178010 | Result | Rodriguez-Bano J, Pano-Pardo JR, Alvarez-Rocha L, Asensio A, Calbo E, Cercenado E, Cisneros JM, Cobo J, Delgado O, Garnacho-Montero J, Grau S, Horcajada JP, Hornero A, Murillas-Angoiti J, Oliver A, Padilla B, Pasquau J, Pujol M, Ruiz-Garbajosa P, San Juan R, Sierra R; Grupo de Estudio de la Infeccion Hospitalaria-Sociedad Espanola de Enfermedades Infecciosas y Microbiologia Clinica; Sociedad Espanola de Farmacia Hospitalaria; Sociedad Espanola de Medicina Preventiva, Salud Publica e Higiene. [Programs for optimizing the use of antibiotics (PROA) in Spanish hospitals: GEIH-SEIMC, SEFH and SEMPSPH consensus document]. Enferm Infecc Microbiol Clin. 2012 Jan;30(1):22.e1-22.e23. doi: 10.1016/j.eimc.2011.09.018. Epub 2011 Dec 15. Spanish. |
| 23774344 | Result | Mosier MJ, Ton-That H. Making the case for de-escalation therapy in ventilator-associated pneumonia once again. Crit Care Med. 2013 Jul;41(7):1810-1. doi: 10.1097/CCM.0b013e31828ce949. No abstract available. |
| 23737333 | Result | Kaye KS. Antimicrobial de-escalation strategies in hospitalized patients with pneumonia, intra-abdominal infections, and bacteremia. J Hosp Med. 2012;7 Suppl 1:S13-21. doi: 10.1002/jhm.983. |
| 12435223 | Result | Gaynes R. Health care--associated bloodstream infections: a change in thinking. Ann Intern Med. 2002 Nov 19;137(10):850-1. doi: 10.7326/0003-4819-137-10-200211190-00015. No abstract available. |
| 15757584 | Result | Cisneros-Herreros JM, Sanchez-Gonzalez M, Prados-Blanco MT, Llanos-Rodriguez C, Vigil-Martin E, Soto-Espinosa de los Monteros B, Pachon-Diaza J. [Blood cultures in the emergency department]. Enferm Infecc Microbiol Clin. 2005 Mar;23(3):135-9. doi: 10.1157/13072162. Spanish. |
| 15814879 | Result | Fridkin SK, Hageman JC, Morrison M, Sanza LT, Como-Sabetti K, Jernigan JA, Harriman K, Harrison LH, Lynfield R, Farley MM; Active Bacterial Core Surveillance Program of the Emerging Infections Program Network. Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med. 2005 Apr 7;352(14):1436-44. doi: 10.1056/NEJMoa043252. |
| 15004058 | Result | Rodriguez-Bano J, Navarro MD, Romero L, Martinez-Martinez L, Muniain MA, Perea EJ, Perez-Cano R, Pascual A. Epidemiology and clinical features of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in nonhospitalized patients. J Clin Microbiol. 2004 Mar;42(3):1089-94. doi: 10.1128/JCM.42.3.1089-1094.2004. |
| 25455590 | Result | Al-Hasan MN, Juhn YJ, Bang DW, Yang HJ, Baddour LM. External validation of bloodstream infection mortality risk score in a population-based cohort. Clin Microbiol Infect. 2014 Sep;20(9):886-91. doi: 10.1111/1469-0691.12607. Epub 2014 Mar 26. |
| 23190091 | Result | Al-Hasan MN, Lahr BD, Eckel-Passow JE, Baddour LM. Predictive scoring model of mortality in Gram-negative bloodstream infection. Clin Microbiol Infect. 2013 Oct;19(10):948-54. doi: 10.1111/1469-0691.12085. Epub 2012 Nov 27. |
| 22005999 | Result | Retamar P, Portillo MM, Lopez-Prieto MD, Rodriguez-Lopez F, de Cueto M, Garcia MV, Gomez MJ, Del Arco A, Munoz A, Sanchez-Porto A, Torres-Tortosa M, Martin-Aspas A, Arroyo A, Garcia-Figueras C, Acosta F, Corzo JE, Leon-Ruiz L, Escobar-Lara T, Rodriguez-Bano J; SAEI/SAMPAC Bacteremia Group. Impact of inadequate empirical therapy on the mortality of patients with bloodstream infections: a propensity score-based analysis. Antimicrob Agents Chemother. 2012 Jan;56(1):472-8. doi: 10.1128/AAC.00462-11. Epub 2011 Oct 17. |
| 23883281 | Result | Retamar P, Lopez-Prieto MD, Natera C, de Cueto M, Nuno E, Herrero M, Fernandez-Sanchez F, Munoz A, Tellez F, Becerril B, Garcia-Tapia A, Carazo I, Moya R, Corzo JE, Leon L, Munoz L, Rodriguez-Bano J; Sociedad Andaluza de Enfermedades Infecciosas/Sociedad Andaluza de Microbiologia y Parasitologia Clinica and Red Espanola de Investigacion en Enfermedades Infecciosas (SAEI/SAMPAC/REIPI) Bacteremia Group; Rodriguez-Lopez F, Garcia MV, Fernandez-Galan V, del Arco A, Perez-Santos MJ, Sanchez Porto A, Torres-Tortosa M, Martin-Aspas A, Arroyo A, Garcia-Figueras C, Acosta F, Florez C, Navas P, Escobar-Lara T. Reappraisal of the outcome of healthcare-associated and community-acquired bacteramia: a prospective cohort study. BMC Infect Dis. 2013 Jul 24;13:344. doi: 10.1186/1471-2334-13-344. |
| 25008770 | Result | Retamar P, Lopez-Prieto MD, Rodriguez-Lopez F, de Cueto M, Garcia MV, Gonzalez-Galan V, Del Arco A, Perez-Santos MJ, Tellez-Perez F, Becerril-Carral B, Martin-Aspas A, Arroyo A, Perez-Cortes S, Acosta F, Florez C, Leon-Ruiz L, Munoz-Medina L, Rodriguez-Bano J; SAEI/SAMPAC/REIPI Bacteremia Group. Predictors of early mortality in very elderly patients with bacteremia: a prospective multicenter cohort. Int J Infect Dis. 2014 Sep;26:83-7. doi: 10.1016/j.ijid.2014.04.029. Epub 2014 Jul 5. |
| 40632893 | Derived | De la Rosa-Riestra S, Gutierrez-Gutierrez B, Lopez-Hernandez I, Perez-Rodriguez MT, Goikoetxea Agirre J, Plata A, Leon E, Farinas Alvarez MC, Fernandez-Natal I, Fernandez-Suarez J, Boix-Palop L, Cuquet Pedragosa J, Jover-Saenz A, Calvo JMS, Martin-Aspas A, Natera-Kindelan C, Del Arco-Jimenez A, Perez-Crespo PMM, Lopez-Cortes LE, Rodriguez-Bano J. External validation of the predictive ability of Charson, SOFA, Pitt, INCREMENT-ESBL and bloodstream infection mortality Risk for 30-day-mortality in bacteraemia using the PROBAC cohort data. Infect Dis (Lond). 2025 Nov;57(11):1059-1067. doi: 10.1080/23744235.2025.2527681. Epub 2025 Jul 9. |
| ID | Term |
|---|---|
| D016470 | Bacteremia |
| D018805 | Sepsis |
| ID | Term |
|---|---|
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided