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With the stem cell transplanting increasing, patients which effected with gut GVHD were also increased. To evaluation the safety and efficacy of FMT for gut GVHD,patients with gut GVHD were recruited.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fecal microbiota | Biological | fecal microbiota transplantation |
| Measure | Description | Time Frame |
|---|---|---|
| times of stool | Change from stool times in a week | 24hours,48hours,72hours, 96hours,fifth day,sixth day, a week |
| Measure | Description | Time Frame |
|---|---|---|
| volume in milliliter of stool | Change from stool volume in a week | 24hours,48hours,72hours, 96hours,fifth day,sixth day, a week |
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Inclusion Criteria:
Exclusion Criteria:
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After stem cell transplantating , some patients suffered the gut GVHD were recuited
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| xiaofei qi | Contact | 1-86-512-67780410 | qixiaofei@suda.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| depei wu | first affiliated of Soochow university | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ä¸å›½ | Recruiting | Suzhou | Jiangsu | 215006 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36352455 | Derived | Liu Y, Zhao Y, Qi J, Ma X, Qi X, Wu D, Xu Y. Fecal microbiota transplantation combined with ruxolitinib as a salvage treatment for intestinal steroid-refractory acute GVHD. Exp Hematol Oncol. 2022 Nov 9;11(1):96. doi: 10.1186/s40164-022-00350-6. | |
| 34220825 | Derived | Zhao Y, Li X, Zhou Y, Gao J, Jiao Y, Zhu B, Wu D, Qi X. Safety and Efficacy of Fecal Microbiota Transplantation for Grade IV Steroid Refractory GI-GvHD Patients: Interim Results From FMT2017002 Trial. Front Immunol. 2021 Jun 17;12:678476. doi: 10.3389/fimmu.2021.678476. eCollection 2021. |
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| ID | Term |
|---|---|
| D000069467 | Fecal Microbiota Transplantation |
| ID | Term |
|---|---|
| D001691 | Biological Therapy |
| D013812 | Therapeutics |
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| 30319644 | Derived | Qi X, Li X, Zhao Y, Wu X, Chen F, Ma X, Zhang F, Wu D. Treating Steroid Refractory Intestinal Acute Graft-vs.-Host Disease With Fecal Microbiota Transplantation: A Pilot Study. Front Immunol. 2018 Sep 25;9:2195. doi: 10.3389/fimmu.2018.02195. eCollection 2018. |