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| Name | Class |
|---|---|
| University of Glasgow | OTHER |
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This pilot randomised controlled trial will directly compare the effect of isometric exercise to isotonic exercise over a period of 12 weeks for participants with a clinical diagnosis of Greater Trochanteric Pain Syndrome (GTPS).
Pain at the side of the hip over or around the greater trochanter of the femur has previously been termed as Greater Trochanteric Pain Syndrome (GTPS). Recent research has found that it is normally due to the gluteal tendons being torn or injured and is often termed as 'gluteal tendinopathy'. GTPS predominantly affects adults aged 40-60 years and is the second most common condition affecting the hip region after osteoarthritis. Quality of life scores are similar to those with advanced hip osteoarthritis but despite its prevalence and disease burden the most effective treatment for this problem is currently unknown.
Numerous studies have shown that exercise programmes are the most effective treatment for other lower limb tendon problems, particularly the Achilles and patella. These programmes typically last a minimum of 12 weeks and are often prescribed by physiotherapists as first-line treatment. However, there is currently limited evidence to support exercise for gluteal tendinopathy. The study plans to directly compare two different types of exercise programmes for those with GTPS for a period of 12 weeks. One group will receive an isometric exercise programme (where the muscle length does not change) and a second group an isotonic exercise programme (where the muscle length does change).
The primary outcome measure which will be used has recently been validated for patients with gluteal tendinopathy and measures function and disability. Additional secondary outcome measures will evaluate aspects relating to quality of life, physical activity and pain. Both groups will be compared at the start of the study and at different times up to a maximum of 12 weeks to help determine if one exercise programme is better than the other.
The results of this pilot study will also help to identify whether a larger trial would be possible in the future.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Isometric exercise | Experimental | 12 week Isometric exercise programme - two exercises (one side-lying and the other standing); six repetitions of each with muscle contraction sustained for 30 seconds. Exercises performed once daily with each session lasting no longer than 10 minutes. |
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| Isotonic exercise | Experimental | 12 week Isotonic exercise programme - two exercises (one side-lying and the other standing); each exercise - 3 sets of 10 repetitions, each repetition 6 seconds duration. Exercises performed once daily with each session lasting no longer than 10 minutes. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Isometric exercise programme | Other | Exercise programme where the muscle length and joint angle do not change due to the limb being held in a static position |
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| Measure | Description | Time Frame |
|---|---|---|
| Measure of disability | Change in score on Victorian Institute of Sport Assessment-Gluteal (VISA-G) questionnaire | Baseline, 4 weeks and 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of Life | Change in score on European Quality of Life (EQ-5D-5L) questionnaire | Baseline, 4 weeks and 12 weeks |
| Perceived change in hip pain | Change in score on Global Rating of Change (GROC) Scale |
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Inclusion Criteria:
Able to give written informed consent
Lateral hip pain for greater than 3 months
Pain on direct palpation of the gluteal tendon insertion on the greater trochanter and additionally at least one of the following pain provocation tests must also be positive:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Neal Millar, PhD FRCSEd | University of Glasgow | Study Director |
| Lorna Paul, MPhil PhD | Glasgow Caledonian University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NHS Greater Glasgow and Clyde | Glasgow | United Kingdom |
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| Isotonic exercise programme | Other | Exercise programme where both the muscle length and joint angle do change, consisting of concentric muscle actions (where the muscle shortens) and eccentric muscle actions (where the muscle lengthens) |
|
| Baseline, 4 weeks and 12 weeks |
| Pain intensity | Change in score on Numeric Pain Rating Scale (NPRS) | Baseline, 4 weeks and 12 weeks |
| Pain catastrophisation | Change in score on Pain Catastrophising Scale | Baseline, 4 weeks and 12 weeks |
| Hip disability | Change in score on Hip Disability and Osteoarthritis Outcome Score (HOOS) | Baseline, 4 weeks and 12 weeks |
| Physical activity | Change in score on International Physical Activity Questionnaire Short Form (IPAQ-SF) | Baseline, 4 weeks and 12 weeks |