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The work hyposesis is based on the application of a chlorhexidine gel against the non-application on the healing abutments in patients who have received a submerged titanium implant to check its effect on healing and prevention of bacterial plaque accumulation during a period of 1 month.
Once the implants are integrated, and given the consent, the patients will be operated to connect the healing abutments as they come from the manufacturer (Mozo Grau, Ticare®). Patients will follow the study protocol in 2 arms.
The random distribution is made prior to assignment following the internet program https://www.random.org
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test (clorhexidine gel) | Active Comparator | The healing abutments were covered by a chlorhexidine gel after the first week of the second surgery (2-stage implants). |
|
| Placebo | Placebo Comparator | The healing abutments were covered without any antiseptic gel after the first week of the second surgery (2-stage implants). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chlorhexidine | Drug | Healing abutment with Clorhexidine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Degree of inflammation | Degree of inflammation was measured using a 4-point Likert scaleInflammation 0 = non-inflamed gingiva with pale pink color. Inflammation 1 = erythematous gingiva without bleeding on manipulation. Inflammation 2 = gingiva with slight bleeding during manipulation during unscrewing or screwing of the abutment. Inflammation 3 = gingiva with heavy bleeding during manipulation during unscrewing or screwing of the abutment. | 1 month after second surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Arturo Sánchez-Pérez, Professor | Universidad de Murcia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Odontologic Universitary Clinic | Murcia | 30008 | Spain |
Non-personal data
After the publication of the results
Any interested researcher
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| ID | Term |
|---|---|
| D057873 | Peri-Implantitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D002710 | Chlorhexidine |
| ID | Term |
|---|---|
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
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After the first week, the healling abutment will be randomly distributed in a test group with application of chlorhexidine gel or a control group without the application of the chlorhexidine gel.
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Double blindness performed for patients and for statistical analysis
| Placebo | Other | Healing abutment without any antiseptic |
|