Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Assessment of short-term outcomes of ipsilateral lobe arterial devascularization of the large hepatocellular carcinoma: single center non-randomized trial.
Assessment of the 30-day mortality and major complications as well as the tumor size changes of the patients undergoing ipsilateral lobe arterial devascularization of the large hepatocellular carcinoma. This is a prospective non randomized trial carried out at the Ribat University Hospital between April 2017 to March 2018.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Devascularization | Experimental | Patients undergoing ipsilateral hepatic artery ligation with extrahepatic collaterals division (HALED) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HALED | Procedure | This is attained via a laparotomy involves isolation of the arterial blood supply of the tumor-containing liver lobe (the ipsilateral hepatic artery as well as the extrahepatic arterial collaterals) while preserving the feeding veins. |
| Measure | Description | Time Frame |
|---|---|---|
| Short term mortality rate | Percentage of patients' postoperative deaths | 30 day |
| Measure | Description | Time Frame |
|---|---|---|
| Short term major complications' rate | Incidence of Clavien/Dindo grade 3 or more postoperative complications | 30 days |
| Tumor response rate according to mRECIST criteria. | Estimation of the residual percentage of viable tumor following the devascularization. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Osama M Elsanousi, MD | Contact | +249 1222 29574 | osamagreen55@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Osama M Elsanousi, MD | Faculty of Medicine. The National Ribat University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ribat University Hospital | Recruiting | Khartoum | 11111 | Sudan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31265917 | Derived | Elsanousi OM, Mohamed MA, Salim FH, Adam EA. Selective devascularization treatment for large hepatocellular carcinoma: Stage 2A IDEAL prospective case series. Int J Surg. 2019 Aug;68:134-141. doi: 10.1016/j.ijsu.2019.06.014. Epub 2019 Jun 29. |
Not provided
Not provided
Not provided
From June 2018 - December 2018
Free
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Jun 28, 2018 | |
| Reset | Jan 11, 2019 | |
| Release | Jan 13, 2019 | |
| Reset | Apr 12, 2019 | |
| Release | May 6, 2019 | |
| Reset | May 6, 2019 | |
| Release | May 11, 2019 | |
| Reset | May 14, 2019 | |
| Release | Jun 27, 2019 | |
| Reset | Jul 2, 2019 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jun 28, 2018 | Jan 11, 2019 | |||
| Jan 13, 2019 |
| ID | Term |
|---|---|
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
Not provided
Not provided
Prospective and non-randomized clinical trial
Not provided
Not provided
Not provided
Not provided
| 30 days |
| Apr 12, 2019 |
| May 6, 2019 | May 6, 2019 |
| May 11, 2019 | May 14, 2019 |
| Jun 27, 2019 | Jul 2, 2019 |
| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
| D008107 | Liver Diseases |