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Worldwide Data suggest that Iodine deficiency is a concern among healthy pregnant women. Thus, screening first trimester healthy pregnant women for iodine status is of clinical value for mother and child as iodine deficiency might have implications on thyroid function as well as pregnancy outcomes
New emerging data suggest pregnant women in Israel are iodine deficient in the first trimester of pregnancy. This is of major concern as first trimester iodine sufficiency is critical for the development of the fetal brain. Our aim is to evaluate iodine consumption in first trimester pregnant women in Israel through dietary questioners, Urinary iodine samples and thyroid functions test assessed through blood samples. All data will be analyzed in a central lab.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| First trimester pregnant women |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Urine sample for iodine measurement | Diagnostic Test | Women will be required to give a urine sample for iodine measurement |
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of average iodine consumption in food | Iodine consumption will be evaluated trough detailed food questionnaires. Data will be quantified and reported in micrograms per day | 1 year |
| Evaluation of urinary iodine concentration | Women will give a spot urine sample for urinary iodine concentration measurement. All data will be analyzed and reported in micrograms/L. Data obtained will be compared to World Health Organization requirements | 1 year |
| Thyroid function test measurement | Thyroid function will be evaluated through blood tests in the first trimester of pregnancy. Data will be analyzed in accordance with local guidelines. | 1 year |
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Inclusion Criteria: First trimester pregnant women with a singleton pregnancy
Exclusion Criteria:
Female
First trimester pregnant women in Israel
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tal Schiller, MD | Contact | 972-8-9441315 | talsc1@clalit.org.il |
| Name | Affiliation | Role |
|---|---|---|
| Viviana Ostrovsky, MD | Clalit Health Services | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Women Health Service | Recruiting | Ashdod | Israel |
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| ID | Term |
|---|---|
| D007037 | Hypothyroidism |
| D013959 | Thyroid Diseases |
| ID | Term |
|---|---|
| D004700 | Endocrine System Diseases |
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| Women Health Center | Not yet recruiting | Tel Aviv | Israel |
|