Carbapenems De-escalation as Antimicrobial Stewardship | NCT03114358 | Trialant

Carbapenems De-escalation as Antimicrobial Stewardship | NCT03114358 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Early carbapenems de-escalation	Experimental	De-escalation carbapenems within 24 hours or no later than 72 hours of prescription by Infectious disease specialist (early de-escalation).	Other: Early Carbapenem de-escalation
Late carbapenems de-escalation	No Intervention	De-escalation followed the hospital policy in which carbapenems were evaluated by ID specialist at 72 hours of admission (late de-escalation). De-escalation may occurred earlier depends upon the decision of the primary care team

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Early Carbapenem de-escalation	Other	The intervention group is de-escalation carbapenems early within 24 hours or no later than 72 hours of prescription by ID specialist (early de-escalation).

Outcomes Module

Secondary Outcomes

Measure	Description	Time Frame
Mortality rate	Compare the mortality rate between 2 groups	90 days
Readmission within 30 days,	Compare the rate of readmission within 30 days between 2 groups