Studying Cognition in SPG4

Studying Cognition in SPG4 Compared to Healthy Controls

Comparing the cognitive levels of patients with SPG4 mutations to healthy controls.

Comparing the cognitive levels of patients with SPG4 mutations to healthy controls by using the CANTAB® and MoCA.

Inclusion Criteria:

• Patient with SPG4 with known SPAST-Mutation (patient group) or healthy control
• Age 18 to 70 years
• Written, informed consent

Exclusion Criteria:

• Lack of ability for a written, informed consent
• Presence of gait disorder or other neurological condition (for healthy controls)