Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging

Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Prospective Multicenter Clinical Trial With Multimodality MR Imaging

To evaluate the efficacy of multi-modality magnetic resonance quantitative parameters in evaluating the treatment effects of high-grade gliomas, and to provide new biomarkers for the establishment of new diagnostic criteria for the identification of true and pseudoprogression of high-grade gliomas.

Inclusion Criteria:

1. Patients with high-grade gliomas confirmed by pathology and have not been treated with concurrent chemoradiotherapy;
2. Written informed consent is obtained.

Exclusion Criteria:

1. Patients not suitable for enhanced MRI scanning of patients;
2. Patients who have not finished follow-up concurrent chemoradiotherapy or MR scanning.