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Cervical cancer is the third most common genital cancer worldwide. The diagnosis of cervical cancer is performed with the cervical biopsy which is guided by the colposcopy. The colposcopy guided cervical biopsy creates pain and several methods have been reported to overcome the pain related with this procedure. Local anesthetic agent injection into the cervix has been studied and found to be effective and also, forced coughing was compared with local anesthetic injection and it is found to be more effective. In fact local injections can create the pain by itself.However no study compared the effect of forced coughing to local anesthetic spray. The study aims to evaluate the comparison of forced coughing with local anesthetic spray with respect to perceived pain during colposcopy guided biopsy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| colposcopic biopsy under local anesthetic sp | Placebo Comparator |
| |
| Patients underwent colposcopic biopsy under forced coughing | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| local lidocaine spray | Drug | The lidocaine spray will be introduced to the cervix just before the biopsy procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain during procedure evaluated by the 0-10 cm scale of Visual analog scale (VAS) scoring system | The perceived pain will be measured during the biopsy procedure. It will be evaluated by the 0-10 cm scale of VAS scoring system. The patient will be asked to rate her pain as 0 corresponds ''no pain'' and 10 to the '' worst pain'' | 0-1 min |
| Measure | Description | Time Frame |
|---|---|---|
| Pain at the 30th minutes after the procedure evaluated by the 0-10 cm scale of VAS scoring system | The perceived pain will be measured after the biopsy procedure (at the 30th min). It will be evaluated by the 0-10 cm scale of VAS scoring system. The patient will be asked to rate her pain as 0 corresponds ''no pain'' and 10 to the '' worst pain'' | 30. Min |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yuzuncu Yil University, Medical faculty, department of obstetric and gynecology | Van | 65000 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D010146 | Pain |
| D003371 | Cough |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012120 | Respiration Disorders |
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The participants will be blinded to the methods used for pain relief.
| forced coughing | Other | The patients will be asked to forced coughing during the biopsy procedure |
|
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |