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The aim of this study is to investigate the changes of amino acid metabolic profiles in different nutritional stages of preterm infants and determine the effects of nutritional intervention on the amino acid metabolic status of preterm infants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Extremely preterm infants |
| ||
| Very preterm infants |
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| Moderately preterm infants |
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| Late preterm infants |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Collection of blood and urine | Other | Collection of blood and urine before nutritional support, during total parenteral nutrition, during partial parenteral nutrition and during enteral nutrition |
| Measure | Description | Time Frame |
|---|---|---|
| Amino acid profiles in blood | Amino acid levels in blood | through the transition to enteral nutrition, an average of 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Weight | Until the corrected gestational age is 37 weeks or discharged | |
| Height | Until the corrected gestational age is 37 weeks or discharged | |
| Head circumference |
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Inclusion Criteria:
Premature infants, and admitted to hospital within 24 hours after birth; Documentation of informed consent; In need of receiving parenteral nutrition after birth;
Exclusion Criteria:
Premature infants with a parenteral nutrition period of less than 3 days; Inborn error of metabolism; Chromosomal abnormalities or multiple malformations;
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Preterm infants who experience various nutritional stages including total parenteral nutrition, partial parenteral nutrition and enteral nutrition
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| Name | Affiliation | Role |
|---|---|---|
| Zhenjuan He, master | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine | Shanghai | China |
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| ID | Term |
|---|---|
| D047928 | Premature Birth |
| ID | Term |
|---|---|
| D007752 | Obstetric Labor, Premature |
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| ID | Term |
|---|---|
| D014554 | Urination |
| ID | Term |
|---|---|
| D014553 | Urinary Tract Physiological Phenomena |
| D012101 | Reproductive and Urinary Physiological Phenomena |
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| Until the corrected gestational age is 37 weeks or discharged |
| D000091642 | Urogenital Diseases |