Group A streptococcal (GAS) pharyngitis in children represents a frequent diagnostic challenge in pediatric emergency departments, since isolated signs and clinical prediction rules are insufficient to accurately discriminate between GAS and non GAS infections. Rapid antigen detection tests (RADTs) therefore remain essential, simple and rapid tools, allowing for rapid GAS identification and prompt antibiotic prescription. However, their sensitivity is not optimal. The aim of the present study is to test the accuracy of a new fluorescent immunoassay (Sofia Strep A FIA) using the optical technology for GAS detection in children 3-15 years old with pharyngitis, compared to a standard RADT, using throat culture as the gold standard (or PCR for discrepant results, i.e. negative culture with any positive RADT).

Inclusion Criteria:

• Patient age between 3 and 15 years
• Clinical diagnosis of pharyngitis
• McIsaac score ≥2

Exclusion Criteria:

• Antibiotic treatment in the two weeks preceding the consultation

Children 3 to 15 years old presenting to the PED with pharyngitis and Mc Isaac score ≥ 2