Heart Rate Variability Under Propofol and Sevoflurane

Spectral Analysis of Heart Rate Variability at BIS 25 and BIS 55 Under Propofol or Sevoflurane

Patients were randomized into 2 groups according to the anesthetic, propofol or sevoflurane. Induction and maintenance were standardized, and after the end of surgery, two steady-state recordings were performed at BIS 25 and BIS 55. Bispectral Index and ECG were continuously recorded and cardiac autonomic nervous activity was investigated using spectral analysis of RR Interval variability

Inclusion Criteria:

• ASA risk classification 1 or 2,
• scheduled for middle ear surgery, or cardiovascular ANS activity.

Exclusion Criteria:

• preoperative medications that interfere with the autonomic nervous system
• preoperative medications that interfere with the central nervous system