Light Therapy and Binge Eating Disorder Treatment (BED Light Study)

Interest of Light Therapy in the Treatment of Binge Eating Disorder: Prospective Controlled Randomized Double-blind Trial

Binge Eating Disorder (BED) is the most widespread food behavior disorder, with prevalence three times higher than anorexia. Its pathophysiology remains poorly understood and the investigators have few therapeutic options. Following a review of the literature, the investigators hypothesize that luminotherapy could be an innovative treatment of BED by its favorable effect on triggers of hyperphagic access, circadian disturbances, attention and impulsivity. The study is prospective, interventional, randomized, double-blind, monocentric (HCL). 52 patients with BED will be randomized to an active arm with intensive luminotherapy (1 daily 30 min, 10,000 lux in the morning) versus a placebo arm (<500 lux). Treatment will be delver every day during 30 days. Assessments will take place on D0, D30 and D60. The main objective is to compare the evolution of the number of hyperphagic access before and after treatment between the two groups. Secondary objectives are to compare characteristics of hyperphagic access, bodily concerns, food dependence and impulsivity, mood, anxiety, cognitive and attentional profiles (STROOP, Go / No Go, SST, BART, Prospective Time Estimation Task, Switching Task), liking / wanted for different food categories and carbohydrate metabolism (CRP, glucose, insulinemia, insulin resistance, profile of lipid abnormalities, 25-OH vitamin D3).

Inclusion Criteria:

• Aged between 18 and 55 years old
• Binge eating disorders or other eating disorders according to DSM V criteria
• Patient with BES score (with " Bing Eating Scale " ) > 18
• Patient with BMI > 18.5 kg/m2
• Patient who agrees to be included in the study and who signs the informed consent form
• Patient affiliated to a healthcare insurance plan

Exclusion Criteria:

• Patients with other psychiatric comorbidities, including a disorder bipolar mood
• Unstabilized diabetic patient with or retinopathy
• Patient with sleep disorder (delay or phase inversion)
• Patient with psychotropic treatment unstabilized (except anxiolytic treatment)
• Recent eye surgery or eye problem preventing exposure to bright light.
• Medication making the skin more sensitive to light (eg. Tablets against malaria)
• Patient who does not understand French/is unable to give consent
• Mentally unbalanced patients, under supervision or guardianship
• Patient already included in a research study
• Pregnancy or desire to be pregnant during the study