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The analysis of the systolic function (contractility) of the right ventricle (RV) is fundamental and central in many pathologies in intensive care unit. It can guide physicians in choosing therapeutics. The conventional ultrasound markers of RV function evaluation currently used are influenced by RV loading conditions, impairing their capacity to approximate a true contractility analysis. Myocardial strain imaging is a recent echographic technique that allows, among other things, to evaluate RV systolic function. It is a reproducible index with early variations which, if it proved to be independent pre-load, would help to better appreciate the RV contractility.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ultrasound measurements | Other | ultrasound measurements of myocardial deformation of free wall right ventricle during a sharp decline of right ventricle preload induced during a session of Intermittent hemodialysis. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultrasound measurements | Procedure | ultrasound measurements of myocardial deformation of free wall right ventricle at 4 time points during a session of intermittent hemodialysis : before the intermittent hemodialysis connection, just after starting hemodialysis, after 1 hour of hemodialysis and 5 minutes before restitution |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of the change in the Longitudinal strain of the free wall right ventricle | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of the change in S' right ventricle wave | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
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Inclusion Criteria:
Exclusion Criteria:
Patients with heart disease (valvular, ischemic, rhythmic)
Patients with ejection fraction of left ventricular altered <45%
Chronic dialysis patients
Patients referred in Articles L. 1121-5, L.1121-6, L.1121-7, L.1121-8 of the Public Health Code:
Patients not willing to participate in the study
Patients not affiliated to a social security
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| Name | Affiliation | Role |
|---|---|---|
| Zoé Schmitt | Hôpital de la Croix-Rousse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital de la Croix Rousse | Lyon | 69004 | France | |||
| Hopital Saint Joseph Saint Luc |
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| ID | Term |
|---|---|
| D013180 | Sprains and Strains |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
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|
| Evaluation of the change in tricuspid annular plane systolic excursion (TAPSE) |
measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound |
| at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Evaluation of the change in visual left ventricular ejection fraction (LVEF) | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Evaluation of the change in mitral E wave | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Evaluation of the change in mitral A wave | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Evaluation of the change in wave E ' at the lateral mitral ring | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Evaluation of the change in systolic fraction of pulmonary venous flow | measurements will be performed using an ultrasound device usually used in our center for the hemodynamic monitoring of patients in intensive care by transthoracic cardiac ultrasound | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| inter individual variability of Longitudinal strain of the free wall right ventricle | Each measurement will be performed by two blind operators | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| intra individual variability of Longitudinal strain of the free wall right ventricle | Each measurement will be performed by two blind operators | at baseline, 1 minute after starting hemodialysis, 1 hour after, and 5 minutes before restitution |
| Lyon |
| 69007 |
| France |