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the study is searching if there is a relationship between the blood groups and RH and the skeletal malocclusion using the skeletal class I as a control group
The study will be conducted on the patients seeking medical care in the orthodontic department Cairo University, for six months all patients with class II and class III malocclusion will be recruited based on Wits appraisal measured from the cephalometric X-ray taken routinely during orthodontic examination. Then a group of class I arch length discrepancy patients will be used as control. A blood sample will be withdrawn and taken to the Cairo university laboratory to analyze the blood group and RH .a statistical analysis will be performed to detect a relationship between skeletal malocclusion and the blood groups as compared to the control
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| skeletal class II subjects | patients with wits appraisal more than 3 mm measured on a cephalometric x ray obtained during diagnosis |
| |
| skeletal class III subjects | patients with wits appraisal less than -3 mm measured on a cephalometric x ray obtained during diagnosis |
| |
| skeletal class I patients | patients with Wits appraisal between -3 and +3 that is measured from a cephalometric x ray obtained during diagnosis of arch length discrepancy. this group will serve as control and obtained after recruitment of the other 2 groups in 1 to 1 fashion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blood type test | Diagnostic Test | a blood sample will be withdrawn from the subjects tested by anti A anti B and anti D antigens to detect the individuals blood group and RH. then statistical analysis to detect presence of a relationship between skeletal types of malocclusion and ABO blood groups |
| Measure | Description | Time Frame |
|---|---|---|
| relationship between blood group and skeletal malocclusion | If skeletal malocclusion subjects were found to have a high percentage of a certain blood type or RH when compared to the control group it will be reported that there is a relationship between blood group and skeletal malocclusion. If percentages of blood groups are approximately the same in the malocclusion subjects and the control then the investigator will report that there is no relationship between blood groups and skeletal malocclusion | the recruitment will be for six months |
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Inclusion Criteria:
skeletal class I,II and III patients non syndromic patients above the age of 18 no previous surgical intervention for correction of skeletal malocclusion
Exclusion Criteria:
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all patients with skeletal malovclusion seeking medical care in the orthodontic department of cairo university for six months
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Noor Elsebai | Contact | 01023415842 | noorelsebai@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Amgad qaddah, professor | head of department of orthodontics cairo university | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Flannery, P. M. (1969). Loyola eCommons The Abo Human Blood Groups and Skeletal Class IIi Malocclusions. | ||
| Background | Schnibben, C. L. (1968). Loyola eCommons A Study of the Relationships of the ABO Human Blood Groups , the Rh Factor and Hereditary Malocclusions of the Skeletal Type , Class II , Division 1. | ||
| 19753252 | Background | Gheisari R, Ghoreishian M, Movahedian B, Roozbehi A. The association between blood groups and maxillofacial deformities. Indian J Plast Surg. 2008 Jul;41(2):138-40. doi: 10.4103/0970-0358.44921. | |
| Background | Science, D. (2015). International Journal of Pharma and Bio Sciences ISSN CRANIOFACIAL MORPHOLOGY WITH GENETIC INFLUENCE OF ABO BLOOD, 6(4), 412±418. |
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| ID | Term |
|---|---|
| D057887 | Overbite |
| D008313 | Malocclusion, Angle Class III |
| ID | Term |
|---|---|
| D008312 | Malocclusion, Angle Class II |
| D008310 | Malocclusion |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D001788 | Blood Grouping and Crossmatching |
| ID | Term |
|---|---|
| D006403 | Hematologic Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| D006650 | Histocompatibility Testing |
| D007159 | Immunologic Tests |
| D000094902 | Blood Banking |
| D001793 | Blood Preservation |
| D014021 | Tissue Preservation |
| D011309 | Preservation, Biological |
| D013812 | Therapeutics |
| D008919 | Investigative Techniques |
| D007158 | Immunologic Techniques |