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| ID | Type | Description | Link |
|---|---|---|---|
| cebd | Other Identifier | center of evidence based/cu |
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This study compared the efficiency of pulp revascularization and MTA apexification in the treatment of patients with necrotic immature anterior teeth.
the participants with 66 anterior necrotic immature teeth were randomly assigned into two equal groups with 33 teeth per each, according to regeneration and MTA apexification. At the first visit, all teeth were accessed and irrigated with NaOCl then a TAP was applied as intra-appointment intracanal medication. At the second visit, after removal of the medication with the irrigation, bleeding was initiated into the canal and isolated by the MTA in the orifice in the regeneration group. While in the Apexification group, the MTA was packed apically and all teeth were finally restored with resin composite restorations. The patients were recalled after 1, 3, 6, and 9 months for clinical and radiographic follow up.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Revascularization | Experimental | Blood clot initiation and grey MTA ( Mineral Tri-oxide Aggregate) cervically compacted. |
|
| Apexfication | Active Comparator | Apexification using grey MTA apically compacted without mechanical preparation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| revascularization | Procedure | a sterile sharp needle was used to irritate the apical tissue until bleeding occurred apically in the root canal space so as to create a biological scaffold for the regenerative process |
| Measure | Description | Time Frame |
|---|---|---|
| Pain intensity measures | self reported pain intesity at 4, 12, 24, and 48 hours.(0= no pain and 100=worst pain) with a scale from 0 to 100 after the two visits. | 2 days |
| Measure | Description | Time Frame |
|---|---|---|
| Resolution of periapical pathosis | Radiographically: by comparing radiolucencies in 9 months postoperative radiograph to the baseline radiograph. | 9 months |
| Amount of radiographic increase in root length: |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| ahmed alkhadem, lecturer | evidence based center, Cairo University | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25443280 | Result | Saoud TM, Zaazou A, Nabil A, Moussa S, Lin LM, Gibbs JL. Clinical and radiographic outcomes of traumatized immature permanent necrotic teeth after revascularization/revitalization therapy. J Endod. 2014 Dec;40(12):1946-52. doi: 10.1016/j.joen.2014.08.023. Epub 2014 Oct 16. | |
| 25069909 | Result | Alobaid AS, Cortes LM, Lo J, Nguyen TT, Albert J, Abu-Melha AS, Lin LM, Gibbs JL. Radiographic and clinical outcomes of the treatment of immature permanent teeth by revascularization or apexification: a pilot retrospective cohort study. J Endod. 2014 Aug;40(8):1063-70. doi: 10.1016/j.joen.2014.02.016. Epub 2014 Jun 13. |
| Label | URL |
|---|---|
| test link | View source |
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| ID | Term |
|---|---|
| D003790 | Dental Pulp Necrosis |
| ID | Term |
|---|---|
| D003788 | Dental Pulp Diseases |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
| D009336 | Necrosis |
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| ID | Term |
|---|---|
| D012038 | Regeneration |
| D056624 | Apexification |
| ID | Term |
|---|---|
| D001686 | Biological Phenomena |
| D012390 | Root Canal Therapy |
| D004708 | Endodontics |
| D003813 | Dentistry |
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participants are allocated at random to receive one of two interventions according to the research plan. In RCT the outcomes are measured, so it is considered a quantitative study . This trial conforms to the Consolidated Standard of Reporting Trials (CONSORT)statement.
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For the allocation concealment mechanism, each of 66 papers (each paper was eight folded) numbered from 1 to 66 were, individually packed, in opaque envelopes. Each participant picked an envelope at the beginning of the second visit. The number in the envelope determined which procedure was to be performed for the patient. The partner was to decide the procedure for the operator according to that number.
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| Apexification | Procedure | a 3-5 mm thickness of MTA using a hand plugger and was verified radiographically. |
|
Root length was measured as a straight line from the cement-enamel junction to the radiographic apex of the tooth in millimeters = (9months follow up length - baseline length)
| baseline and 9 months |
| Amount of radiographic increase in the root dentinal wall thickness: | Dentin thickness was measured by =root thickness-pulp space and compared to the baseline radiograph measurements. | baseline and 9 months |
| Decrease of apical diameter: | the diameter of the apical foramen was measured in millimeters and compared to the baseline radiograph measurements | baseline and 9 months |
| test link | View source |
| D010335 |
| Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |