The Multi-disciplinary Treatment of Functional Gut Disorders Study

The MANTRA Study: The Multi-disciplinary Treatment of Functional Gut Disorders Study

Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders. Patients will be followed up to end of clinic treatment and 12 months beyond the end of treatment. Symptoms, quality of life, costs to the healthcare system and psychological outcomes will be assessed.

Inclusion Criteria:

• Functional gastrointestinal disorder as defined by Rome IV

Exclusion Criteria:

• Diagnosed or suspicion of organic gastrointestinal disorder (ie Coeliac, IBD)
• Age <18 or >80
• Non-English speaking
• Patient's from outside of metropolitan Melbourne who cannot attend clinic visits
• Prominent eating disorder
• Chronic opioid dependence
• Medications which can explain functional gut symptoms
• Surgery of GI tract that can explain functional gut symptoms
• Major, non-GI, organ dysfunction
• Pregnancy
• Major Psychiatric disorder