Influences of Multivitamin Supplementation on Health Parameters

Influence of Liquid Multivitamin Supplementation on Life Quality, Mood, Perception of Stress and Health-related Vital and Blood Parameters and the Immune System

In this study the investigator will evaluate whether a liquid multivitamin supplement influences blood and vital parameters. Furthermore the investigator will establish the effects on life quality, mood and perception of stress and will characterize changes on immune system.

The double-blind, randomized intervention study is conducted for 12 weeks and includes two groups (placebo versus verum) with same number of participants.

The investigator aims to determine the effects of multivitamin supplement on blood and vital parameters which includes blood pressure, pulse, heart rate, variability of heart rate, vitamin D, vitamin B12, folic acid, homocysteine, HbA1c. Furthermore the investigator will access life quality, mood and perception of stress through the following questionnaire POMS, PSS-10, SF12 & SF36. The investigator will evaluate whether the multivitamin supplement changes the frequency of diseases like cold which represents the function of the immune system.

Inclusion Criteria:

• healthy women and men
• age between 30-60 years
• employed

Exclusion Criteria:

• acute and chronic diseases (including diabetes, inflammatory bowel diseases, dementia, multiple sclerosis)
• frequent use of alcohol, drugs or cigarettes (>5 cigarettes / day)
• use of additional supplements
• use of medications (e.g. antihypertensive medications, lipid reducers, thyroid medication)