Frequency of Hemorrhages Associated With the Functional Anomalies of Willebrand Factor in Emergency Patients

Study of the Frequency of Hemorrhages Associated With the Functional Anomalies of Willebrand Factor in Emergency Patients of a Veino Arterial or Veinous ECMO

ECMO has improved the outcome of heart or respiratory failure and carcinogenic shock and are increasingly used. However bleeding complications occurring in up to 50% of patients are poorly understood and worsen the overall results. The aim is to investigate the occurence of bleeding and its frequency according to the type of ECMO either veno-arterial or veno-venous. The investigators also want to assess the relation of bleeding with von Willebrand Factor defects.

Inclusion Criteria:

• informed consent of patient or person in charge
• patient supplied by an ECMO for cardiac or respiratory failure and referred to Lille University Hospital
• patient affiliated to "french social security"

Exclusion Criteria:

• pregnant woman
• no consent
• no affiliation to
• patient affiliated to '
• preexisting bleeding disorders