The Interactive Physical and Cognitive Exercise System

The Interactive Physical and Cognitive Exercise System (iPACES™): A Neuro-exergame for Preventing Alzheimer's and Ameliorating Cognitive Impairment

This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise. In particular, this study will investigate the possible benefits of physical exercise (such as pedaling an under-table stationary elliptical) or mental exercise (such as playing a videogame on a portable tablet), or combining these activities together (as in the iPACES™ exergame).

Inclusion Criteria:

• co-residing older adults (e.g., spouses, partners, roommates, relatives)
• both at least 50 years of age
• normative/typical cognitive function or those with Mild Cognitive Impairment (MCI) or mild Neurocognitive Disorder (mNCD) or early Alzheimer's disease
• adequate vision and dexterity for on-screen assessments
• able to pedal an under-table elliptical
• permission of primary care provider and cardiologist (if applicable)

Exclusion Criteria:

• history of seizure
• Parkinson's disease
• significant dementia/memory loss