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The SYNTAX score (SS) has been recommended by clinical guideline and appropriate use criteria for coronary revascularization (CR) to provide guidance on optimal treatment strategies for patients with stable coronary artery diseases (CAD). However, discrepancy in SS between angiographic core lab (ACL) and cardiologists has been found. Whether the misestimate will lead to inappropriate CR and whether a SS intervention will improve CR appropriateness in patients with stable CAD remain unknown.
Thus, our study aims at evaluating whether a real-time feedback from ACL rightafter the angiographies will improve CR appropriateness. A before-and-after controlled trial was designed. In the first period of time, stable CAD patients undergoing elective coronary angiographies with at least one coronary lesion stenosis ≥ 50% from one Chinese cardiac center will be continuously recruited as the control group. In the second period, eligible patients will be recruited continuously and a real-time SS category feedback from ACL rightafter the angiography will be given to the cardiologists. Appropriateness of treatment strategies in two groups will be analyzed to determine whether a real-time SS feedback can improve the treatment appropriateness. The appropriateness of treatment strategies will be adjudicated by Chinese version appropriate use criteria for CR.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SYNTAX score category feedback group | Experimental | A real-time SYNTAX score category feedback from angiographic core lab will be given to the cardiologists rightafter the angiographies. |
|
| Controlled group | No Intervention | Cardiologists' subjective SYNTAX score category judgement will be recorded during the angiography. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| real-time feedback of SYNTAX score category | Diagnostic Test |
|
| Measure | Description | Time Frame |
|---|---|---|
| Inappropriate rate of coronary revascularization | Inappropriate rate will be adjudicated by Chinese appropriate use criteria for coronary revascularization. | 1 month after study completion |
| Measure | Description | Time Frame |
|---|---|---|
| The proportion of inappropriate PCI | Inappropriate rate of percutaneous coronary intervention (PCI) will be adjudicated by Chinese appropriate use criteria for coronary revascularization. | 1 month after study completion |
| The proportion of inappropriate CABG |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| China National Center for Cardiovascular Diseases | Beijing | Beijing Municipality | 100037 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32452896 | Derived | Lin S, Zhang H, Chen SP, Rao CF, Wu F, Zhou FJ, Wang Y, Yan HB, Dou KF, Wu YJ, Tang YD, Xie LH, Guan CD, Xu B, Zheng Z. Mis-estimation of coronary lesions and rectification by SYNTAX score feedback for coronary revascularization appropriateness. Chin Med J (Engl). 2020 Jun 5;133(11):1276-1284. doi: 10.1097/CM9.0000000000000827. |
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Inappropriate rate of coronary artery bypass graft (CABG) will be adjudicated by Chinese appropriate use criteria for coronary revascularization. |
| 1 month after study completion |
| The proportion of utilizing PCI procedures | The proportion of patients who undergo percutaneous coronary intervention (PCI) among total patients | 1 month after study completion |
| The proportion of utilizing CABG procedures | The proportion of patients who undergo coronary artery bypass graft (CABG) among total patients | 1 month after study completion |