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The purpose of this study is to determine whether microwave ablation is more effective in the treatment of simple renal cysts than conventional laparoscopic decortication.
Background: Simple renal cysts are the most common renal masses, and occur in half of all patients older than 50 years.They are usually asymptomatic and benign, asymptomatic and discovered incidentally. However, over time, these simple cysts can enlarge, become symptomatic and develop complications, requiring intervention.They can be managed by a variety of surgical and percutaneous methods, including percutaneous aspiration (with or without injection of a sclerosing agent), endoscopic marsupialization or excision, open surgery and laparoscopic cyst excision.Percutaneous aspiration and sclerotherapy have been described as safe and effective methods of managing symptomatic simple renal cysts without the cost and morbidity associated with conventional surgery and laparoscopy.However, laparoscopic decortications and simple aspiration is associated with a high recurrence rate because the cyst wall epithelium is responsible for active liquid production.
Purpose:To determine whether microwave ablation is more effective in the treatment of simple renal cysts than conventional laparoscopic decortication.
Method:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| laparoscopic microwave ablation | Experimental | laparoscopic microwave ablation will be performed before the renal cysts are decorticated |
|
| percutaneous microwave ablation | Experimental | percutaneous microwave ablation will be performed to treat the renal cysts without decorticating. |
|
| laparoscopic decortication | Active Comparator | conventional laparoscopic decortication will be performed to treat the renal cysts. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| microwave ablation | Procedure | KY2000 microwave ablation system was used in the experimental group. A power output of 60 W for 1-3 min for 1-3 cycles to treat the renal cysts according to the cysts size and classification.Percutaneous microwave ablation will be performed under the guidance of ultrasound while the laparoscopic microwave ablation will be performed under direct vision |
| Measure | Description | Time Frame |
|---|---|---|
| local recurrence | 12 months postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative complications | postoperativeļ¼up to 30 days | |
| operative time | during operation | |
| Hospital stay time |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yonghui Chen | Contact | cyh1488@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Yiran Huang | Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yonghui Chen | Recruiting | Shanghai | Shanghai Municipality | China |
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| ID | Term |
|---|---|
| D052177 | Kidney Diseases, Cystic |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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|
| laparoscopic decortication | Procedure | conventional laparoscopic decortication will be performed to treat the renal cysts |
|
| time from the date of admission until the date of discharge, up to 2 weeks |
| quality of life assessed by quality of life questionnaire | postoperativeļ¼up to 6 months |
| change from baseline glomerular filtration rate (GFR) of the affected kidney, 12 months minus baseline | baseline and 12 months |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |