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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A01684-41 | Other Identifier | ID-RCB number, ANSM |
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insufficient inclusion rate
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OBJECTIVES: To investigate whether respiratory variations of the inferior vena cava (ΔIVC) and internal jugular vein (ΔIJV) diameters during standardized breathing (ΔIVCST and ΔIJVST) increase after a therapeutic bleeding in spontaneously breathing and obese patients with dysmetabolic hyperferricemia.
DESIGN: Prospective, monocentric study in the EFS Nord-de-France blood center.
PATIENTS: Obese patients with dysmetabolic hyperferricemia undergoing a therapeutic bleeding.
INTERVENTIONS: The investigators performed ultrasound measures and collected clinical parameters before and after a therapeutic bleeding, during a standardized respiratory maneuver.
MAIN OUTCOME AND MEASURES: The primary endpoint was the ΔIVCST change induced by a 300 to 500ml therapeutic bleeding. The investigators measured the minimal and maximal IVC and IJV diameters during a standardized respiratory maneuver. ΔIVCST and ΔIJVST were calculated as follows: [(maximal diameter - minimal diameter)/maximal diameter].100.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| obese patients with dysmetabolic hyperferritinemia | PATIENTS: obese patients with dysmetabolic hyperferritinemia undergoing a therapeutic bleeding. INTERVENTIONS: The investigators performed ultrasound measurements (echography) and collected clinical parameters before and after a 300 to 500ml therapeutic bleeding, during a standardized respiratory maneuver. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| echography | Procedure | The inferior vena cava and the internal jugular vein diameters were measured by echography before and after blood withdrawal during a standardized respiratory maneuver |
| Measure | Description | Time Frame |
|---|---|---|
| blood withdrawal-induced changes in the respiratory variations of the inferior vena cava during a standardized respiratory maneuver (ΔIVCST) | The primary endpoint was the ΔIVCST change induced by a 300 to 500ml therapeutic bleeding. The investigators measured the minimal and maximal IVC diameters during a standardized ventilation. ΔIVCST was calculated as follows: [(maximal diameter - minimal diameter)/maximal diameter].100. | during a standardized respiratory maneuver, an average 1 hour maximum |
| Measure | Description | Time Frame |
|---|---|---|
| blood withdrawal-induced changes in the respiratory variations of the internal jugular vein during a standardized respiratory maneuver (ΔIJVST) | The primary endpoint was the ΔIJVST change induced by a 300 to 500ml therapeutic bleeding. The investigators measured the minimal and maximal IJV diameters during a standardized ventilation. ΔIJVST was calculated as follows: [(maximal diameter - minimal diameter)/maximal diameter].100. |
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Inclusion Criteria:
Exclusion Criteria:
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Obese patients with dysmetabolic hyperferritinemia
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| Name | Affiliation | Role |
|---|---|---|
| Sébastien Preau, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Roger Salengro, CHRU de Lille | Lille | France |
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| ID | Term |
|---|---|
| D000085583 | Hyperferritinemia |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D019189 | Iron Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D050177 | Overweight |
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| ID | Term |
|---|---|
| D019220 | High-Energy Shock Waves |
| ID | Term |
|---|---|
| D000069453 | Ultrasonic Waves |
| D013016 | Sound |
| D011840 | Radiation, Nonionizing |
| D011827 | Radiation |
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| during a standardized respiratory maneuver, an average 1 hour maximum |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D055585 |
| Physical Phenomena |