Exploration of the Mechanism of Movement Improvement During RBD in Parkinson's Disease Using NIRS

Exploration of the Mechanism of Movement Improvement During Rapid Eye Movement (REM) Sleep Behaviour Disorder (RBD) in Parkinson's Disease Using Near-infrared Spectroscopy (NIRS)

The purpose of this study is to confirm the improvement of movement during RBD in Parkinson's disease and to explore the neuronal network involved in this improvement using NIRS.

The aim of this study is to compare the quality of movement during REM sleep during RBD episodes and movement awake without and with dopaminergic treatment while measuring cortical activity using NIRS.

Inclusion Criteria:

• Idiopathic Parkinson's Disease (Hughes AJ et al., 2001)
• Patients with REM sleep behaviour sleep disorder according to the ICSD2 (International Classification of Sleep Disorders 2) criteria and frequent reported several times per week by the spouse
• Informed written consent signed
• Patient aged 40 to 90 years
• Affiliate or benefiting from a social security scheme.

Exclusion Criteria:

• Atypical Parkinson's Syndromes

• Patient not accepting polysomnography

  • Contraindications to cerebral Magnetic Resonnance Imaging (MRI): pacemaker, cochlear implants, certain heart valves, claustrophobia, pregnancy.
  • Limit of validity of the MRI: if the patient presents dyskinesias preventing immobile maintenance of a few minutes in the MRI for the acquisition of images