Metoclopramide for Post-Traumatic Headache. A Pilot Study

Metoclopramide for Post-Traumatic Headache. A Pilot Study

Post-traumatic headache is common. We are determining short and longer-term outcomes among patients treated for post-traumatic headache with IV metoclopramide.

Inclusion Criteria:

• Traumatic injury to the head has occurred
• Headache has developed within 7 days of injury to the head
• Headache is not better accounted for by another diagnosis (eg, previous history of migraine or tension-type headache)
• The headache must be rated as moderate or severe in intensity at the time of initial evaluation.
• The plan of the attending emergency physician must include treatment with parenteral metoclopramide.

Exclusion Criteria:

• Patients will be excluded if more than ten days have elapsed since the head trauma, if the headache has already been treated with an anti-dopaminergic medication, or for medication contra-indications including pheochromocytoma, seizure disorder, Parkinson's disease, use of monoamine oxidase inhibitors, and use of anti-rejection transplant medications. Patients will not be excluded for pregnancy or breast-feeding.