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| Name | Class |
|---|---|
| Guy's and St Thomas' NHS Foundation Trust | OTHER |
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Sampling of accessed root canals with endodontic paper points during treatment and immediately pre-obturation of endodontic root canals was carried out.
Following ethical approval (REC ref: 05/Q0705/051), informed consent was obtained from patients undergoing root canal treatment.The teeth included in the study had been referred to a specialist centre for the treatment of endodontic infection. They all responded negatively to vitality tests and presented pre-operative apical radiolucencies. The source population were referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital, King's College London Dental Institute.Treatments on the teeth were carried out by a total of 19 postgraduate endodontic students.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Primary treatments | Patients undergoing primary root canal treatments. Only teeth which have not previously been accessed are included in this cohort.The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital |
| |
| Re-treatments | Patients undergoing re-treatments. Only teeth which had a previous root canal treatment which failed are included in this cohort.The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Detection of residual vital bacteria in the root canal space | Diagnostic Test | Detection of residual vital bacteria in the root canal space. No intervention, as it is an observational study. Vital bacteria are looked for in the samples taken from the root canal space. |
| Measure | Description | Time Frame |
|---|---|---|
| Detection of residual bacteria during and post root canal treatment | Using a vital fluorescent stain bacteria sampled from the root canal space were detected during and post root canal treatment. | June 2016 |
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Inclusion Criteria:
Exclusion Criteria:
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The source population are adults aged 18-65, referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital, King's College London Dental Institute. Both single- and multi-rooted non-vital teeth are included in the study
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Federico Foschi, Dr | Contact | +44 (0)020 7188 7188 | federico.foschi@kcl.ac.uk | |
| Dylan Herzog, Mr | Contact | +44 (0)207 188 1789 | dylan.b.herzog@kcl.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Federico Foschi, Dr | King's College London | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| King's College London, Dental Institute, Floor 22, Endodontics | Recruiting | London | London | SE1 9RT | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28530469 | Derived | Herzog DB, Hosny NA, Niazi SA, Koller G, Cook RJ, Foschi F, Watson TF, Mannocci F, Festy F. Rapid Bacterial Detection during Endodontic Treatment. J Dent Res. 2017 Jun;96(6):626-632. doi: 10.1177/0022034517691723. Epub 2017 Feb 1. |
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IPD is not planned to be made available to other researchers as of yet
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