Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Acute myocardial infarction (AMI) pose a pool clinical outcome to men and women whom treatment was delayed. However, reperfusion time was limited in previous studies. To evaluate the system delay and clinical outcomes among Chinese patients with AMI, consecutive inpatient case prospectively collected from 1999 to 2016. Basic data and innovative evidence will accelerate evidence-based clinical practice and policy making, and improve AMI patients outcomes finally.
AMI is one of the leading causes of mortality and morbidity in public health globally, as well as in China. Remarkable variations of repercussion time and clinical outcome have been noted, however little information is available about how shortened D2B time is incorporated appropriately into routine clinical practice in China. In addition, basic data and evidence about effectiveness of treatment for AMI during long-term recovery is limited. Practical and applied knowledge from large unselected population is needed to guide practice for improvement.
This study will enroll patients with a confirmed diagnosis of AMI consecutively in China. At study entry, participants will be interviewed during their index hospitalization, to collect information about symptoms, functioning, quality of life, and medical care. Demographic characteristics, medical history, clinical features, diagnostic tests, medications, procedures, and in-hospital outcomes of patients will be abstracted from medical records by well trained professional abstractors. At 1 month, and 12 month after discharge, participants will return to the clinic for follow up visits. This study will examine system delay that may affect patients recovery after a heart attack. Effective clinic path system, and risk model for AMI patients will be established based on the findings, to improve patients outcomes in future finally.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | The patient received reperfusion therapy between 1999 January 1 and 2009 December 31 |
| |
| Group 2 | The patient received reperfusion therapy between 2010 January 1 and 2016 December 31 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Reperfusion | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| 30-Day Freedom From Mortality | All-cause death | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| 12-Month Freedom From Major Adverse Cardiac Events (MACE) | Composite of MACE including cardiac death, non-fatal AMI, and clinically driven target vessel revascularization. | 12 months |
| Cardiac death |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
In China, hospitalized patients with acute myocardial infarction will be enrolled consecutively.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Shaoliang Chen, PhD | Nanjing First Hospital, Nanjing Medical University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Changshu First People's Hospital | Changshu | Jiangsu | China | |||
| Changzhou Traditional Chinese Medicine Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30755362 | Derived | Xue X, Kan J, Zhang JJ, Tian N, Ye F, Yang S, Qu H, Chen SL; MOODY trial investigators. Comparison in Prevalence, Predictors, and Clinical Outcome of VSR Versus FWR after Acute Myocardial Infarction: The Prospective, Multicenter Registry MOODY Trial-Heart Rupture Analysis. Cardiovasc Revasc Med. 2019 Dec;20(12):1158-1164. doi: 10.1016/j.carrev.2019.01.023. Epub 2019 Jan 23. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Death that could not be attributed to a noncardiac etiology was considered cardiac death.
| 12 months |
| Myocardial infarction | Myocardial infarction was diagnosed by electrocardiographic changes and/or a rise and fall of creatine kinase-myocardial band fraction in the presence of ischemic symptoms. | 12 months |
| Target vessel revascularization | Target vessel revascularization was defined as repeated revascularization by PCI or surgery of the target vessel. | 12 months |
| Changzhou |
| Jiangsu |
| China |
| Jintan People's Hospital | Jintan | Jiangsu | China |
| Liyang Hospital of TCM | Liyang | Jiangsu | China |
| Gaochun People's Hospital | Nanjing | Jiangsu | China |
| Anqing First People's Hospital | Anqing | China |
| The 123 Hospital of PLA | Bengbu | China |
| Changzhou Fouth People's Hospital | Changzhou | China |
| Huaian Second People's Hospital | Huai'an | China |
| Huainan Eastern Hospital | Huainan | China |
| Huainan Xinhua Hospital | Huainan | China |
| Maanshan Shiqiye Hospital | Ma’anshan | China |
| Muyang Traditional Chinese Medicine Hospital | Muyang | China |
| Nanjing First Hospital | Nanjing | China |
| Nanjing Pukou Central Hospital | Nanjing | China |
| Nnajing 81 Hospital | Nanjing | China |
| Nnajing Integrated Traditional Chinese and Westem Medicine Hospital | Nanjing | China |
| Taicang First People's Hospital | Taicang | China |
| Wuxi Third Hospital | Wuxi | China |
| Yixin People's Hospital | Wuxi | China |
| Yixing Traditional Chinese Medicine Hospital | Wuxi | China |
| Xuncheng Central Hospital | Xuancheng | China |
| Zhangjiagang First People's Hospital | Zhangjiagang | China |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D015424 | Reperfusion |
| ID | Term |
|---|---|
| D013504 | Cardiovascular Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D010477 | Perfusion |
| D008919 | Investigative Techniques |
Not provided
Not provided