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The purpose of the study is the prospective and standardized data collection of patients treated with ion therapy at MedAustron.
During and up to 10 years after radiation therapy data regarding tumor control and treatment response as well as acute and late toxicities will be collected at regular time intervals. Additionally quality of life and sociodemographic status will be assessed in all study patients and neurocognitive assessment will be performed in patients undergoing ion radiation of the brain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ion beam therapy | All patients treated with ion beam therapy at MedAustron who consent to the participation in the registry. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Protons and Carbon Ions | Radiation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Therapy response | Therapy Response according to RECIST Version 1.1 | 10 years |
| Overall survival | 10 years | |
| Progression-free survival | 10 years | |
| Local progression-free survival | 10 years | |
| Cause-specific survival | 10 years | |
| Toxicity according to NCI CTCAE | Acute/late toxicity according to CTCAEv4.03, June 14,2010 | 10 years |
| Measure | Description | Time Frame |
|---|---|---|
| EORTC-QLQ-C30 | Patient-reported quality of life | Through study completion, at 3, 5, and 10 years |
| EORTC-QLQ-BN20 | Patient-reported quality of life for brain cancer patients |
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Inclusion Criteria:
Exclusion Criteria:
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Patients treated with ion beam therapy at MedAustron
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yvonne Goy, MD | Contact | +43 2622 26 100 | 407 | yvonne.goy@medaustron.at |
| Piero Fossati, MD MSc | Contact | +43 2622 26 100 | 408 | piero.fossati@medaustron.at |
| Name | Affiliation | Role |
|---|---|---|
| Yvonne Goy, MD | EBG MedAustron GmbH | Principal Investigator |
| Piero Fossati, MD MSc | EBG MedAustron GmbH | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| EBG MedAustron GmbH | Recruiting | Wiener Neustadt | Lower Austria | 2700 | Austria |
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| ID | Term |
|---|---|
| D011522 | Protons |
| ID | Term |
|---|---|
| D002414 | Cations, Monovalent |
| D002412 | Cations |
| D007477 | Ions |
| D004573 | Electrolytes |
| D007287 |
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| Through study completion, at 3, 5, and 10 years |
| EORTC-QLQ-PR25 | Patient-reported quality of life for prostate cancer patients | Through study completion, at 3, 5, and 10 years |
| Neurocognitive test battery | Change in cognition from baseline to endpoint as measured by standardized subtests of test battery | Through study completion, at 3, 5, and 10 years |
| Inorganic Chemicals |
| D006859 | Hydrogen |
| D004602 | Elements |
| D005740 | Gases |
| D000071940 | Nucleons |
| D004601 | Elementary Particles |
| D055585 | Physical Phenomena |