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| ID | Type | Description | Link |
|---|---|---|---|
| 1985246 | Other Identifier | CNIL |
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The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known. The aim of this study was to evaluated the incidence rate of S. aureus SSI over the years and risk factors of these infections in a french University Hospital.
Surgical site infections (SSI) in orthopedic surgery are responsible for reduced quality of life, increased length of hospital stay and costs. The most commonly identified organism is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known.The aim of this study was to evaluate the incidence rate trend of S. aureus SSI over the years and risk factors of theses infections in a french University Hospital.
The knowledge obtained by this study will enable identification of the surgical patients most at risk of developping S. aureus SSI, and who would probably benefit most from new interventions given prophylactically and specifically to prevent S. aureus infections.
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| Measure | Description | Time Frame |
|---|---|---|
| Risk factors of S. aureus surgical site infections. | univariate analysis of potential risk factors. Data with p value less than 0.1 were included in a logistic regression model | up to 1 year following surgery |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence rate trend of S. aureus SSI over the year. | linear regression slope test of S. aureus SSI incidence rates by years | from january 1st 2012 to april 30th 2015 |
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Patients undergoing orthopedic or traumatologiy surgeries in Grenoble university hospital
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Caroline Landelle, PH | Contact | 0033476765643 | clandelle@chu-grenoble.fr |
| Name | Affiliation | Role |
|---|---|---|
| Caroline landelle, PH | University Hospital, Grenoble | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital, Grenoble Alpes | Recruiting | Grenoble | 38043 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10823564 | Background | Kalmeijer MD, van Nieuwland-Bollen E, Bogaers-Hofman D, de Baere GA. Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery. Infect Control Hosp Epidemiol. 2000 May;21(5):319-23. doi: 10.1086/501763. | |
| 24367612 | Background | Korol E, Johnston K, Waser N, Sifakis F, Jafri HS, Lo M, Kyaw MH. A systematic review of risk factors associated with surgical site infections among surgical patients. PLoS One. 2013 Dec 18;8(12):e83743. doi: 10.1371/journal.pone.0083743. eCollection 2013. |
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| ID | Term |
|---|---|
| D013203 | Staphylococcal Infections |
| D013530 | Surgical Wound Infection |
| D009140 | Musculoskeletal Diseases |
| D007239 | Infections |
| D014946 | Wound Infection |
| D014947 | Wounds and Injuries |
| D011183 | Postoperative Complications |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| ID | Term |
|---|---|
| D001423 | Bacterial Infections and Mycoses |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| 26720215 | Background | Marimuthu K, Eisenring MC, Harbarth S, Troillet N. Epidemiology of Staphylococcus aureus Surgical Site Infections. Surg Infect (Larchmt). 2016 Apr;17(2):229-35. doi: 10.1089/sur.2015.055. Epub 2015 Dec 31. |
| 24835378 | Background | Lepelletier D, Saliou P, Lefebvre A, Lucet JC, Grandbastien B, Bruyere F, Stahl JP, Keita-Perse O, Berthelot P, Aho S; workgroup SF2H. "Preoperative risk management: strategy for Staphylococcus aureus preoperative decolonization" (2013 update). French society of Hospital Hygiene. Med Mal Infect. 2014 Jun;44(6):261-7. doi: 10.1016/j.medmal.2014.04.003. Epub 2014 May 14. No abstract available. |
| 25927093 | Background | Webster J, Osborne S. Preoperative bathing or showering with skin antiseptics to prevent surgical site infection. Cochrane Database Syst Rev. 2015 Feb 20;2015(2):CD004985. doi: 10.1002/14651858.CD004985.pub5. |