Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Dimension Research | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The Precious study is likely to help determine the frequency (percentage) of subclinical hypothyroidism among pregnant women in Pakistan It will also help to determine the risk factors for developing subclinical hypothyroidism during pregnancy
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of subclinical hypothyroidism in pregnant females | Continuous variables with normal and non-normal distributions would be reported as mean (SD) and median [inter-quartile range (IQR)], respectively. Prevalence of subclinical hypothyroidism with 95% confidence Interval (CI) will be calculated. Continuous variables between group will compared by using Independent sample t test, and categorical variables will compare by using the chi-square test. | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| The risk factors that might be associated with subclinical hypothyroidism in all enrolled pregnant patients. | Odds Ratios (OR) and their 95% Confidence Intervals (CI) will be estimated using Logistic Regression. The likelihood ratio test used to assess the association between the explanatory variables and the risk of the subclinical hypothyroidism. Univariable analyses will perform to examine the effect of each variable on the risk of subclinical hypothyroidism. In multivariate analysis all insignificant variables (p >0.05) will check for their confounding and interaction effects before their removal from the final model. |
Not provided
Inclusion Criteria:
Subjects must meet all of the following criteria to be enrolled into the study
Patient between 18-45 years of age; is pregnant and in First Trimester
Patient willing to give blood sample for laboratory testing
Patient willing to provide written authorization to obtain data for the study
Exclusion Criteria:
Patients suffering from any
Subjects with history of non-thyroid malignancy
Patient currently taking medication for hyperthyroidism
Active systemic infection
Patient with physical or mental impairment
Patients on systemic steroid therapy or lithium therapy
Patients in second or third trimester of pregnancy
Patient not willing to give blood sample for laboratory testing
Patient not willing to provide written authorization to obtain data for the study
Not provided
Not provided
Primary Care Clinic/Private Clinic
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Raeefuddin Ahmed, MD | Abbott | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Isra University hospital | Hyderābād | 71800 | Pakistan | |||
| Pakistam Insititute of Medical science |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 12 months |
| Islamabad |
| 144001 |
| Pakistan |
| Atia Hospital Hospital | Karachi | 75100 | Pakistan |
| Boluvard Hospital | Karachi | 75500 | Pakistan |
| MediCell Hospital | Karachi | 75500 | Pakistan |
| Services Hospital | Lahore | 54000 | Pakistan |
| Sir Ganga Ram hospital | Lahore | 54000 | Pakistan |
| Welcare Medical Centre | Muzafferabad, Azad Kashmir | 13100 | Pakistan |
| Lady Reading hospital | Peshawar | 25000 | Pakistan |