The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose disinfection solution.

In this contralateral crossover study, qualifying subjects will wear a total of 2 pairs of study contact lenses. Lenses will be worn according to a randomized lens sequence assignment. Each pair will consist of a test lens (Test 1 or Test 2) and a control lens.

Inclusion Criteria:

• Able to understand and must sign an Informed Consent;
• Successful wearer of spherical soft contact lenses in both eyes for a minimum of 5 days per week and 8 hours per day during the past 3 months;
• Manifest cylinder less than or equal to 1.50 diopter (D) in each eye;
• Best Corrected Visual Acuity (BCVA) 20/25 or better in each eye;
• VA with habitual spectacles 20/40 in both eyes (OU) or better and willing to wear spectacles as needed during the washout period and during study lens exposure;
• Other protocol-specified inclusion criteria may apply.

Exclusion Criteria:

• Any anterior segment infection, inflammation, abnormality or disease that contraindicates contact lens wear;
• Any use of systemic or ocular medications for which contact lens wear could be contraindicated;
• History of refractive surgery or plan to have refractive surgery during the study or irregular cornea in either eye;
• Ocular or intra-ocular surgery (excluding placement of punctal plugs) within the previous 12 months or planned during the study;
• Current or history of pathologically dry eye in either eye that would preclude contact lens wear;
• Current or history of herpetic keratitis in either eye;
• Eye injury in either eye within 12 weeks immediately prior to enrollment;
• History of intolerance or hypersensitivity to any component of the study lenses or solutions;
• Habitual contact lenses worn in an extended wear modality (routinely sleeping in lenses for at least 1 night per week) over the last 3 months prior to enrollment;
• Use of topical ocular medications and artificial tear or rewetting drops that would require instillation during contact lens wear;
• Other protocol-specified exclusion criteria may apply.

This analysis population includes all subjects exposed to any study lens (Safety Analysis Set).

Baseline through study completion, approximately 8 days

An adverse event (AE) is any untoward medical occurrence, unintended disease or injury, or untoward clinical signs in subjects, users, or other persons, whether or not related to the investigational medical device. AEs were obtained through solicited and spontaneous comments from subjects and through observations by the Investigator as outlined in the study protocol. Safety Analysis Set, based on treatment-specific exposure.