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Cerebral hypoperfusion and hypoxia are the major determinants of neurological outcomes following acute brain injury as proved in Traumatic Brain Injury/Sub Arachnoid Haemhorrhage literature. How the brain injury affects cerebral oxygenation in patients with CVT is not currently known. Some of the factors that can affect cerebral oxygenation in patients with CVT are Hemoglobin, PO2, PCO2, Cerebral Perfusion Pressure (or MAP) and change in Intracranial Pressure after Decompressive Craniectomy. This study is designed to study how these factors affect cerebral oxygenation and impact of Decompressive Craniectomy on the cerebral oxygenation.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| NIRS based Cerebral Oximetry | Device | Cerebral Oximetric measurement before and after decompressive craniectomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Ipsilateral Regional Cerebral Oxygen Saturation | Measurement of regional cerebral oxygen saturation over ipsilateral frontal lobe before and after decompressive craniectomy with follow up at postoperative 24 and 48 hours. | From Recruitment till 48 hours postoperative (end of study) |
| Measure | Description | Time Frame |
|---|---|---|
| Contralateral Regional Cerebral Oxygen Saturation | Measurement of regional cerebral oxygen saturation over contralateral frontal lobe before and after decompressive craniectomy with follow up at postoperative 24 and 48 hours. | From Recruitment till 48 hours postoperative (end of study) |
| Systolic Blood Pressure |
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Inclusion Criteria:
-Patients diagnosed with cerebral venous thrombosis, undergoing decompressive craniectomy.
Exclusion Criteria:
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Patients with Cerebral venous thrombosis for Decompressive craniectomy
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NIMHANS | Bengaluru | Karnataka | 560029 | India |
May be shared on individual requests
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| ID | Term |
|---|---|
| D020767 | Intracranial Thrombosis |
| ID | Term |
|---|---|
| D002542 | Intracranial Embolism and Thrombosis |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Measurement of systolic blood pressure before and after decompressive craniectomy with follow up at postoperative 24 and 48 hours. |
| From Recruitment till 48 hours postoperative (end of study) |
| Glasgow coma scale score | Measurement of Glasgow coma scale score before and after decompressive craniectomy with follow up at postoperative 24 and 48 hours. | From Recruitment till 48 hours postoperative (end of study) |
| Arterial blood gas measurement | Arterial blood gas measurement before and after decompressive craniectomy with follow up at postoperative 24 and 48 hours. | From Recruitment till 48 hours postoperative (end of study) |
| Haemoglobin | Haemoglobin measurement before and after decompressive craniectomy with follow up at postoperative 24 and 48 hours. | From Recruitment till 48 hours postoperative (end of study) |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |