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Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider phobia can extend to stimuli which are conceptually similar to spiders (i.e. cockroaches), but have never been presented during the respective treatment.
Fear extinction has evolved as the central mechanism underlying exposure-based treatments. Findings from conditioning studies indicate that fear reduction following a fear extinction procedure can generalize from the extinction stimulus to other conceptually and perceptually related stimuli. This study is aimed at translating these findings to a clinical application and will hence examine whether the basic principles of extinction generalization are applicable to exposure.
Patients with spider phobia will either receive two sessions of in-vivo exposure with spiders or no treatment. Prior to as well as after treatment, patient's fear of spiders will be assessed using the Behavioral Approach Test (BATs) and self-report questionnaires. In addition, BATs with cockroaches will be conducted to examine the effects of exposure therapy on extinction generalization.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exposure Treatment | Experimental | Participants of this arm receive two 60-minute sessions of exposure treatment for spider fear |
|
| No Exposure Treatment | No Intervention | Participants of this arm receive no exposure or other adequate treatment |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exposure treatment for spider fear | Behavioral | Two sessions (each session = 60 minutes) of in-vivo exposure treatment (including psychoeducation) with two different spiders. Exposures comprise a hierarchy of 7 steps, to be completed with both spiders. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the Behavioral Approach Test (BAT) from pre- to posttreatment | Behavioral Approach Tests with Spiders and Cockroaches will be conducted at pre- and posttreatment. Here, the closest proximity a participant is able to attain to the spider/cockroach will be measured. | Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Subjective Fear / Disgust during the Behavioral Approach Tests (BATs) using the Subjective Units of Distress Scale (SUDS) | Subjective Fear / Disgust during the Behavioral Approach will be assessed at the initial and final approach distances to the spider / cockroach during the respective BATs. | Pre-and Posttreatment (with approximately 4 days between pre- and posttreatment) |
| Measure | Description | Time Frame |
|---|---|---|
| Epigenetic / DNA methylation | DNA collection kits at pre- and posttreatment | Pre- and posttreatment (with approximately 4 days between pre- and posttreatment) |
| Depression Anxiety Stress Scales (DASS) |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Armin Zlomuzica, Dr. | Ruhr University of Bochum | Principal Investigator |
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| ID | Term |
|---|---|
| C562465 | Phobia, Specific |
| C000719193 | Arachnophobia |
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| Change in Heart Rate during the Behavioral Approach Tests (BATs) from pre- to posttreatment | During each BAT with spiders and cockroaches, heart rate will be measured. In addition, a 5-minute baseline will be recorded prior to the first BAT at each assessment. | Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment) |
| Change in the Fear of Spiders Questionnaire (FSQ) | Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment) |
| Change in the Spider Phobia Questionnaire (SPQ) | Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment) |
| Change in the Spider Beliefs Questionnaire (SBQ) | Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment) |
| Pretreatment (assessed once prior to treatment) |
| Questionnaire for the Assessment of Disgust Sensitivity (FEE) | Pretreatment (assessed once prior to treatment) |