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| Name | Class |
|---|---|
| Institut National de la Santé Et de la Recherche Médicale, France | OTHER_GOV |
| Association Keoogo | UNKNOWN |
| Institut de Recherche en Sciences de la Sante, Burkina Faso | OTHER_GOV |
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MUAC only is a pilot trial external control carried out between January 2017 and December 2017 in the Yako district (northern region), Burkina Faso.
The objective of this study is to evaluate an integrated protocol for acute malnourished children without medical complication. The hypotheses of the integrated protocol include :
Objectives :
Main objective :
To ensure the recovery rate of the integrated protocol for treatment of acute malnutrition is significantly greater than 75% (reference value of the national program in BF).
Secondary objectives :
Methods :
The study population will include all acutely malnourished children aged between 6 and 59 months seeking consultations at all of the health centers in Yako District between January 2017 and December 2017.
The study will be implemented in Burkina Faso's Yako District, which includes 54 health centers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MUAC<125mm | Experimental | no medical complication |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ready to Use Therapeutic Food (RUTF) | Drug | MUAC used as the primary admission and exit criteria for children with MUAC <125mm and no medical complication. Single treatment of RUTF for severe and moderate malnourished children and gradual reduction of doses according to the MUAC and the weight of the child during treatment. MUAC split into 3 categories:
|
| Measure | Description | Time Frame |
|---|---|---|
| Recovery rate | The recovery is defined as below :
| Between 4 and 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality rate | Between inclusion and week 12 | |
| Default rate | Patient absent for 3 consecutive visits | Between 3 and 12 weeks |
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Inclusion Criteria:
Being between 6 and 59 months old
New admission
Acute malnutrition defined as follows:
Resident in the study area (Yako district)
Signed informed consent of the mother or the child's guardian
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Susan Shepherd, MD | Directrice de recherches Opérationnelles et Médicales, ALIMA, USA | Principal Investigator |
| Renaud Becquet, MPH,PhD,HDR | Chercheur Inserm, Inserm U1219 Bordeaux Population Health Center-Université de Bordeaux | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ALIMA | Yako | Nord Region | Burkina Faso |
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| SOS médecins Burkina Faso |
| UNKNOWN |
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|
|
| Non-respondent rate |
Patient who not reach the recovery criteria after twelve weeks in the program |
| 12 weeks after inclusion |
| Hospitalization rate | Between inclusion and week 12 |
| Relapse rate | Patient having reached the recovery criteria and returning for a new episode of malnutrition (MUAC<125mm). The children's MUAC will be measured at home 3 months after program exit. For organizational and financial reasons, this data will not be collected for all children. A specific protocol explaining the sampling and organization of data collection will be annexed to the protocol. | up to 3 months |
| RUTF rations | Total number of RUTF bags received per child during participation in the program. | Between inclusion and week 12 |