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| ID | Type | Description | Link |
|---|---|---|---|
| 2016-A00845-46 | Other Identifier | Agence Nationale de Sécurité du Médicament et des produits de santé |
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| Name | Class |
|---|---|
| National Institute of Health and Medical Research 1061, Montpellier | UNKNOWN |
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Suicidal behavior (SB) is a major public health problem in France, with over 10,000 suicides (6th in the EU28) and 220,000 suicide attempts (SA) per year. These data seem underestimated by 20%. A large percentage of men (6%) and women (9%) in France made at least one lifetime SA. In addition, SBs are common among young people and are the second leading cause of death among 15-44 year-olds. The interaction of multiple factors in SB complicates the creation of predictive models. These are currently imprecise and prevent the development of consensual recommendations for the management of suicidal patients.
Most suicide attempters are evaluated in the emergency room where it is imperative to identify people with a high risk of relapse. Risk assessment is generally based on the experience of the practitioner who uses psychometric scales as support for clinical decisions. This assessment could be improved and supplemented by other sources of information. Thus, we aim to develop a short and specific tool that combines:
Over 65 months, 5 emergency departments (Montpellier, Nimes, Uzès, Nice, Marseille) will recruit a total of 650 patients who attempted suicide.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neuropsychological battery tests | Other | All participants performed the same evaluation: clinical and neuropsychological assessment. All of them are suicide attempters without psychotic features |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Neuropsychological battery tests | Behavioral | The neuropsychological battery tests is composed with: Continuous Performance Test, Iowa Gambling Test, Verbal fluency (animals), Emotional stroop, Self-injury implicit association test and N-back test. The neuropsychological battery assesses domains heavily involved in suicidal behavior: impulsivity, affective dysregulation, alterations in decision-making (risky choices), selective attention,verbal fluidity and working memory. |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of suicidal relapse according to aggressive impulsivity. | aggressive impulsivity will be assessed by the capacity to inhibit responses during a Continuous Performance Task (CPT) | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Score of a short scale of suicidal risk assessment | We aim to identify predictive factors of the occurrence of suicidal behavior in a non-psychotic suicidal population, in order to develop a battery of short-term tests applicable to emergencies. This short term tests will allow to establish a multidimensional score for the prediction of the risk of relapse. | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jorge LOPEZ-CASTROMAN, MD | Contact | +33 4 66 68 34 26 | jorge.lopezcastroman@chu-nimes.fr |
| Name | Affiliation | Role |
|---|---|---|
| Jorge LOPEZ-CASTROMAN, MD | Centre Hospitalier Universitaire de Nīmes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Montpellier University Hospital | Recruiting | Montpellier | 34295 | France |
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| ID | Term |
|---|---|
| D013406 | Suicide, Attempted |
| D004630 | Emergencies |
| D059020 | Suicidal Ideation |
| ID | Term |
|---|---|
| D013405 | Suicide |
| D016728 | Self-Injurious Behavior |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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|
| Intensity of suicidal ideation assessed by the Columbia Suicide Severity Rating Scale (C-SSRS) | We aim to identify predictive factors of the occurrence of suicidal behavior in a non-psychotic suicidal population, in order to develop a battery of short-term tests applicable to emergencies. This short term tests will allow to establish a multidimensional score for the prediction of the risk of relapse | 12 months |
| Characteristics of suicidal behaviors assessed by Columbia Suicide History Form and the Columbia Suicide Severity Rating Scale | We aim to identify predictive factors of the occurrence of suicidal behavior in a non-psychotic suicidal population, in order to develop a battery of short-term tests applicable to emergencies. This short term tests will allow to establish a multidimensional score for the prediction of the risk of relapse | 12 months |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |