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Patients who underwent laparoscopic repair of large hiatal hernias and anterior fundoplication with mesh are examined for their recurrence rate one year after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient cohort | Patients who underwent laparoscopic hernia repair of giant hiatal hernia with mesh and received anterior fundoplication |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| repair of giant hiatal hernia with mesh and anterior fundoplication | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Radiological recurrence rate of hiatal hernia determined by computer tomography (CT) scan | To evaluate the radiological recurrence rate of hiatal hernia at least one year after surgery by performing a computer tomography | minimum 1 year after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life by GIQLI | Estimate the quality of life using a standardized questionnaire (Gastrointestinal Qualitiy of Life Index = GIQLI) at least one year after surgery | minimum 1 year after surgery |
| Clinical outcome |
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Inclusion Criteria:
Exclusion Criteria:
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Inclusion of all patients older than 18 years with initial large hiatal hernia (>20% herniated into thoracic cavity) and laparoscopic hiatoplasty with mesh and anterior fundoplication
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| Name | Affiliation | Role |
|---|---|---|
| Urs Zingg | Principal Investigator | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39304965 | Derived | Susstrunk J, Stimpfle D, Wilhelm A, Ghielmini EM, Potthast S, Zingg U. Clinical and computed tomography outcomes after mesh-enforced hiatoplasty and anterior hemi-fundoplication in large hiatal hernia repair. World J Surg. 2024 Nov;48(11):2669-2677. doi: 10.1002/wjs.12354. Epub 2024 Sep 20. |
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| ID | Term |
|---|---|
| D009074 | Melanocyte-Stimulating Hormones |
| ID | Term |
|---|---|
| D053486 | Melanocortins |
| D011333 | Pro-Opiomelanocortin |
| D007028 | Hypothalamic Hormones |
| D036361 | Peptide Hormones |
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Evaluate the clinical outcome at least one year after surgery by examining the patient and asking targeted questions on the symptoms regarding the former hiatal hernia (using visual analogue scale questions on dysphagia, meteorism, bloating, reflux and retrosternal pain). Furthermore the patients are asked about their general satisfaction regarding the performed surgical intervention.
| minimum 1 year after surgery |
| Peri- and postoperative morbidity / mortality | Evaluate the peri- and postoperative morbidity and mortality from the patient records and a clinical examination | minimum 1 year after surgery |
| D006728 |
| Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D010908 | Pituitary Hormones, Anterior |
| D010907 | Pituitary Hormones |
| D009479 | Neuropeptides |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D009419 | Nerve Tissue Proteins |
| D011506 | Proteins |