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Endoscopic radial artery harvesting in coronary bypass surgery is routinely performed by the investigators. In this study, the investigators want to compare the MiFusion TLS2 (Endotrust GmbH, Germany) device to the LigaSure Maryland Jaw (Medtronic, USA). The vessel harvesting is performed in the standard fashion according to the institutional routine. The patients are randomized preoperatively to one of the devices. The proximal end of the radial artery will be preserved and deep-frozen for histological assessment. Endothelial integrity will be investigated using Hematoxylin-Eosin, CD31 and endothelial nitrogen monoxide synthase.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LigaSure endoscopic radial harvesting | Active Comparator | The endoscopic vessel harvesting will be performed using the LigaSure device. |
|
| TLS2 endoscopic radial harvesting | Active Comparator | The endoscopic vessel harvesting will be performed using the TLS2 device. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| LigaSure endoscopic vessel harvesting | Device | The radial artery will be harvested endoscopically using the LigaSure system. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Endothelial integrity of the radial artery using histological examination. | Through study completion, an average of 1 year. |
| Measure | Description | Time Frame |
|---|---|---|
| Harvesting time | The harvesting time will be measured during the vessel harvesting surgery. | |
| Hemostasis in the arm indicated by bleeding from radial artery side branches or veins in the arm. | Intraoperatively and directly after vessel harvesting the arm is controlled using the endoscope and bleeding can be detected during this control. End of surgery is end of this outcome parameter. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Arnaud Van Linden, MD | Kerckhoff Klinik | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kerckhoff Klinik | Bad Nauheim | 61231 | Germany |
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| TLS2 endoscopic vessel harvesting | Device | The radial artery will be harvested endoscopically using the TLS2 system. |
|
| Accuracy of vessel sealing, if side branches of the radial artery are bleeding after blood insufflation, additional clips have to placed at the side branch. | The blood insufflation is performed immediately after vessel harvesting and leaks can be detected. |