Comparison of TrIfecta and Perimount Magna Ease

Prospective Randomized Comparison of TrIfecta and Perimount Magna Ease

The hemodynamic performance of two supraannular aortic xenografts (Trifecta, St. Jude Medical and Perimount Magna Ease, Edwards Lifescience) will be compared using rest- and stress echocardiography in a randomized prospective study. Furthermore, the prostheses' influence on postoperative outcome will be compared using spiroergometry, quality of life questionnaire and heart failure biomarkers.

Inclusion Criteria:

• Patients between 18 and 75 years

• Elective aortic valve replacement in patients with predominant aortic stenosis

  • including concomitant CABG and/or atrial fibrillation ablation and/or supracoronary aortic replacement

• Informed consent including willingness for stress echocardiography, spiroergometry and quality of life examination after 6 months.

• Native German speakers (quality of life questionnaire in German language)

Exclusion Criteria:

• Isolated aortic regurgitation
• Concomitant aortic regurgitation > 2°
• Endocarditis
• LVEF <40%
• Concomitant other valve surgery
• s/p valve surgery
• Contraindication for stress echocardiography