Difficulty in finding suitable patients.

An uncontrolled feasibility study on using mouth piece ventilation in palliation of dyspnea in subjects with incurable advanced disease. Subjects are recruited from a local Hospice and from oncology ward. The main outcomes are the compliance of the subjects with the treatment and alleviation of dyspnea during the treatment period.

Inclusion Criteria:

• at least moderate dyspnea (NRS = Numeric Rating Scale ≥ 4)
• incurable advanced disease
• able to understand the study and to give informed consent
• would not gain from intensive care or resuscitation according to the treating physician

Exclusion Criteria:

• unable to participate and use MPV due to e.g. delirium or lack of co-operation
• the cause of the dyspnea can be succesfully treated
• unable to give informed consent