To compare the effects of various combinations between 6 hertz(Hz) rTMS & LFrTMS on the limb motor dysfunction due to cerebral vascular disease.

It is the basic principle for functional recovery after cerebrovascular disease to restore the original balance in reciprocal inhibition between affected hemisphere and unaffected hemisphere.

repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuroplastic technique rebalancing interhemispheric competition after stroke. Low frequency rTMS (LFrTMS) on contralesional hemisphere or high frequency rTMS (HFrTMS) on lesional hemisphere might be the basic choice.

6 hertz(Hz) primed LFrTMS on lesional primary motor cortex has the stronger effect than LFrTMS alone does on one hand; the other newly-developed combination, i.e. HFrTMS on lesional primary motor cortex and LFrTMS on contralesional primary motor cortex might also be more effective than they do respectively on the other hand.

The main aim of our research is to find out which combination is better by considering both safety and efficiency.

Inclusion Criteria:

• Aged from 30 to 90 years;
• Newly onset cerebral infarction or brain hemorrhage confirmed by MRI or CT;
• the disease duration is less than 20 weeks when recruited into the trial;
• no existence of limb motor dysfunction before this onset, and new occurrence of unilateral limb motor dysfunction after this onset;
• the physical and mental condition are good enough to cooperate with the assessment and treatment;
• the NIHSS score: total 5-20,1a,1b,1c=0;
• the subject or legal guardian sign the consent form.

Exclusion Criteria:

• during pregnancy;
• with skull defect;
• with metal implants, cardiac pacemaker, cochlear implantation;
• epileptiform discharge in EEG.