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| ID | Type | Description | Link |
|---|---|---|---|
| 2006/1217 | Other Identifier | CSET number |
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Fifty patients with squamous cell carcinoma of the larynx T1 or T2N0 will therefore have a 99mTc lymphoscintigraphy per operative. The identified sentinel node will be removed along with the other lymph nodes of the selective group II and III recess. Sentinel lymph node staging alone and complete dissection with routine anatomical pathology will be compared If this technique is reliable it will make a therapeutic de-escalation in the treatment of small tumors of the larynx by limiting the ganglionic gesture in the patients whose sentinel node is free from metastasis and also to better choose the treatment in case of lymph node involvement
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oropharynx | Experimental | Tumors of the oropharynx T1T2N0 treated with radiotherapy |
|
| Larynx | Experimental | Tumors of the T1T2N0 larynx treated by surgery, laser or robot |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Detection and resection of sentinel lymph node | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reliability of the sentinel lymph node technique | Up to 24 months |
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Inclusion Criteria:
Exclusion Criteria:
1) Patient already treated for this tumor outside a biopsy excision, 2) Contraindications to radiotherapy, scintigraphy or procedure, allergy to Rhenium sulphide or 99m Technetium 3) History of epidermoid carcinoma of VADS 4) Pregnant woman, likely to be pregnant or nursing, (5) Persons deprived of their liberty or under guardianship, 6) Impossibility to submit to the medical follow-up of the trial for geographical, social or psychological reasons.
7) Patient who underwent cervical surgery for any cause 8) Patient with cervical radiotherapy 9) Patient unable to undergo cervical lymph node dissection 10) Patient treated for another cancer outside the VADS within a period of less than 6 months.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Antoine MOYA PLANA, MD | Contact | 0142114603 | +33 | antoine.moyaplana@gustaveroussy.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gustave Roussy | Recruiting | Villejuif | Val de Marne | 94805 | France |
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| ID | Term |
|---|---|
| D006258 | Head and Neck Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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