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The investigators aim to study the prevalence of latent tuberculosis infection (LTBI) using whole-blood interferon-r release assays, and determine the risk factors of LTBI in Korean health care workers.
Further study details as provided by Hanyang University Hospital
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| health care workers | Other | health care workers including doctors, nurses, technicians and orderly who were hired in 2016 at the Hanyang University Hospital |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| QFT-IT Test and other blood sampling | Other | In all enrolled health care workers, QFT-IT Test and other blood sampling were performed. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of latent tuberculosis infection developed in Korean health care workers | The participants performed QuaniFERON-TB Gold In-Tube test (QFT-IT test) and blood sampling at enrollment. So, the length of time which from the start of the first test of very first participants to the end of test of very last participant is 3 months. The percentage of participants with LTBI in health care workers was evaluated. | Three months |
| Measure | Description | Time Frame |
|---|---|---|
| Annual incidence of latent tuberculosis infection in Korean health care workers | QFT-IT test was performed at enrollment and repeated at point of one year after enrollment. So, the length of time which from the start of the first test of very first participants to the end of the second test of very last participant is 12 to 15 months. The percentage of participants with positive conversion in follow-up QFT-IT test (second test) was evaluated in participants who had negative results in the first QFT-IT test. Annual infection of LTBI was evaluated with the conversion of QFT-IT test through annual check up of QFT-IT test. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dong Won Park, M.D., Ph.D. | Contact | portrayme@hanmail.net |
| Name | Affiliation | Role |
|---|---|---|
| Jang Won Shon, M.D., Ph.D. | Hanyang University Hospital, Seoul, Korea | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hanyang University Hospital | Recruiting | Seoul | South Korea |
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| ID | Term |
|---|---|
| D055985 | Latent Tuberculosis |
| D014376 | Tuberculosis |
| ID | Term |
|---|---|
| D009164 | Mycobacterium Infections |
| D000193 | Actinomycetales Infections |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
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| 1 year after first QFT-IT test (12-15 months) |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D000085343 | Latent Infection |