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This study evaluates the nitric oxide and arginase levels in patients with dental implants. Peri-implant sulcular fluid and saliva samples were collected after loading of the implants
Nitric oxide (NO) metabolism is associated with the clinical inflammatory state of peri-implant tissues and also affected by the mechanic stimulus. Therefore, The NO content of PISF reflects two different measures and can serve as an indicator of peri-implant soft tissue inflammation and/or bone response to force application and loading Arginase may reduce NO production by depleting the common substrate. Thus, increased salivary arginase activities detected in periodontitis patients may cause decreased NO synthesis and lead to a decrease in the antibacterial property of saliva.
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| Measure | Description | Time Frame |
|---|---|---|
| Biochemical parameters (nitric oxide and arginase) in periimplant sulcular fluid and saliva | The changes in nitric oxide and arginase levels after implant loading were determined. | Baseline and 1, 3 and 6 months after implant loading |
| Measure | Description | Time Frame |
|---|---|---|
| Plaque index | The changes in plaque index after implant loading. Plaque index was recorded for determining and classifying oral hygiene status. | Baseline and 1, 3 and 6 months after implant loading |
| Gingival index |
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Inclusion Criteria:
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Twenty patients with one or more implants restored with fixed crown prostheses
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The changes in gingival index after implant loading. Gingival index was recorded for classifying and evaluating gingival inflammation.
| Baseline and 1, 3 and 6 months after implant loading |
| Probing depth | The changes in probing pocket depth after implant loading.Probing pocket depth was measured for determining periimplant health. | Baseline and 1, 3 and 6 months after implant loading |
| Bleeding on probing | The changes in bleeding on probing after implant loading. Bleeding on probing was recorded for evaluating gingival inflammation. | Baseline and 1, 3 and 6 months after implant loading |