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| Name | Class |
|---|---|
| Kyung Hee University Hospital | OTHER |
| Pusan National University Hospital | OTHER |
| Semyung University Affiliated Oriental Medical Hospital | OTHER |
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The aim of this study is to investigate the short and long term efficacy and the safety of SCRT treatment for PAR
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SCRT group | Experimental | 3g, three times a day, each taken before or between meals |
|
| placebo group | Placebo Comparator | 3g, three times a day, each taken before or between meals |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SCRT | Drug | composed of eight herbs: Glycyrrhiza uralensis Fischer 1g Zingiber officinale Roscoe 0.5g Cinnamomum cassia Blume 0.2g, Ephedra sinica Stapf 0.5g, Pinellia ternata Breitenbach 2.67g, Paeonia lactiflora PALL 1g, Asiasarum sieboldi F. Maekawa 0.5g, Schisandra chinensis 2.67g (per 9g of granules) |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Total Nasal Symptom score | At baseline, week 2, 4, 8, 12 |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) score | At baseline, week 2, 4, 8, 12 | |
| Change from baseline in Total serum IgE level | At baseline, week 4 | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Youme Ko | Contact | 822-961-9278 | iseeymk@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Minhee Kim | Kyung Hee University Hospital at Gangdong | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kyung Hee University Hospital at Gangdong | Recruiting | Seoul | Seoul | 05278 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28963290 | Derived | Kim MH, Ko Y, Ahn JH, Yun Y, Yun MN, Ko SG, Choi I. Efficacy and safety of So-Cheong-Ryong-Tang in treatment of perennial allergic rhinitis: study protocol for a double-blind, randomised, parallel-group, multicentre trial. BMJ Open. 2017 Sep 27;7(9):e016556. doi: 10.1136/bmjopen-2017-016556. |
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| ID | Term |
|---|---|
| D012221 | Rhinitis, Allergic, Perennial |
| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
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| DongGuk University |
| OTHER |
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|
| Placebos | Drug | is made of lactose, corn starch and caramel coloring, and has appearance, shape, weight, taste, and color similar to SCRT |
|
| Change from baseline in eosinophil count |
| At baseline, week 4 |
| Change from baseline in cytokine level | At baseline, week 4 |
| D012130 |
| Respiratory Hypersensitivity |
| D010038 | Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |