Evaluate Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®)

Evaluate Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®) for Intraperitoneal Adhesion in Patient With Gynecological Surgery, a Multicenter Single-blinded, Randomized Study

The purpose of this study is to evaluate the efficacy and safety of Mediclore®, as an antiadhesive barrier, which is made of Poloxamer, Gelatin and Chitosan.

Inclusion Criteria:

• Patients with Gynecological disease (benign disease)
• Patients who Written informed consent
• Patients without clinically significant lab

Exclusion Criteria:

• having enrolled another clinical trials within 1 month
• Immunosuppression or autoimmune disease
• Anticoagulant, general steroids within a week from surgery
• Serious diseases (heart failure, renal failure, liver failure, uncontrolled hypertension, diabetes mellitus, coagulation deficiencies)
• Patients with previous history of surgery at the same operate site