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Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures ultimately resulting in improvised standard of patient care.
These bacteria metabolize different kind of carbohydrates accumulated around orthodontic appliances and create acidic environment in the oral cavity leading to enamel demineralization around the brackets and white spot lesions.
This study was carried out to evaluate and compare the efficacy of probiotic toothpaste and chlorhexidine mouthwash in patients undergoing orthodontic treatment with individuals who are not using them.
INTRODUCTION - When the basic oral hygiene is poor, orthodontic appliances create areas where plaque gets accumulated, especially around brackets, bands, wires, and other attachments; this facilitates the development of white spot lesions. Probiotics act by competitively inhibiting the pathogenic bacteria because they have greater adhesion to the tissues while Chlorhexidine is often used as an active ingredient in mouthwash designed to reduce dental plaque around orthodontic appliances. AIM & OBJECTIVE - The objectives of the study is to evaluate and compare the effects of the topical application of probiotic toothpaste and chlorhexidine mouthwash on the Streptococcus Mutans levels in the plaque of orthodontic patients hence improving the oral micro-flora of oral cavity by competitive inhibition of Streptococcus Mutans in plaque present around brackets.
MATERIAL & METHOD - The study consists of thirty randomly selected orthodontic patients undergoing fixed appliance treatment. The patients were divided into three groups - Control Group (Group 1), Probiotic Toothpaste Group (Group 2) & Chlorhexidine Mouthwash Group (Group 3). Samples were collected at two times interval: before the study began (Phase 1) and after thirty days (Phase 2).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | Active Comparator | They were not given probiotic toothpaste or chlorhexidine mouthwash |
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| Probiotic Group | Experimental | Patients were asked to brush twice daily with given "G.D Probiotic Toothpaste" and were asked not to eat or drink anything for half-an-hour. |
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| Chlorhexidine Mouthwash Group | Experimental | Patients were asked to rinse daily with "Dr. Reddy's Clohex" chlorhexidine mouthwash of 10ml without dilution for three times a day after meals (Breakfast, Lunch Dinner) for 3-4 minutes and were asked not to eat or drink anything for half-an-hour. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotic Toothpaste | Drug | G.D Probiotic Toothpaste bacteriocin Lactic Acid Bacteria |
|
| Measure | Description | Time Frame |
|---|---|---|
| Control Group/Probiotic Toothpaste/Chlorhexidine Mouthwash | Probiotic Toothpaste & Chlorhexidine Mouthwash Reduced S.mutans when compared to Control Group | 1 Month |
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Inclusion Criteria:
Exclusion Criteria:
-Patient with poor periodontal condition Patient with known medical condition e.g. Subacute bacterial, endocarditis , diabetes, valvular disease ,anaemia etc
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| Name | Affiliation | Role |
|---|---|---|
| Dr.Chandrika Dubey, MDS | Peoples University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peoples College Of Dental Science & Research Center | Bhopal | Madhya Pradesh | 462016 | India |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23810047 | Background | Jose JE, Padmanabhan S, Chitharanjan AB. Systemic consumption of probiotic curd and use of probiotic toothpaste to reduce Streptococcus mutans in plaque around orthodontic brackets. Am J Orthod Dentofacial Orthop. 2013 Jul;144(1):67-72. doi: 10.1016/j.ajodo.2013.02.023. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Dec 28, 2016 | |
| Reset | Feb 17, 2017 | |
| Release | Apr 3, 2017 |
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| Dr. Reddy's Clohex | Drug | 0.20% Chlorhexidine Mouthwash |
|
|
| Control Group | Other | No Probiotic toothpaste & Chlorhexidine Mouthwash |
|
| Reset | Jun 15, 2017 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Dec 28, 2016 | Feb 17, 2017 | |||
| Apr 3, 2017 | Jun 15, 2017 |
| ID | Term |
|---|---|
| D000069451 | Long Term Adverse Effects |
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
| D008722 | Methods |
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