Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia in Cancer Surgery

Effect of Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia on Inflammatory Response and Pain Following Radical Cytsectomy

the investigators aim is to investigate the effect of continuous preperitoneal bupivacaine wound infiltration versus epidural analgesia on the inflammatory cytokines response following radical cytectomy

Inclusion Criteria:

• ASA I-III patients
• aged 18-60 yr
• undergo open abdominal cancer surgery

Exclusion Criteria:

• general contraindications for epidural analgesia,
• recent history (8 weeks) of, chemotherapy or radiation,
• chronic opioid use