Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This is a retrospective observational cohort database analysis. The study will review retrospectively the records of patients undergoing a first peripheral blood stem cell mobilization for multiple myeloma in the databases from approximately 15 hospitals which are part of the IFM collaborative group. Patient records will be divided into two groups of 50 patients minimum, maximum 100 patients or up to the number of patient records that could be extracted. The first group of patients will have received plerixafor plus G-CSF without the administration of chemotherapy as a mobilization strategy and a second group of patients will have received cyclophosphamide plus G-CSF as a mobilization strategy.
All consecutive patients with complete set of data (and who underwent apheresis) treated between 2009 and 2013 with G-CSF and plerixafor and all consecutive patients with complete data (and who underwent apheresis) treated between 2009 and 2013 with G-CSF and cyclophosphamide will be included.
All data that will be analyzed will be extracted from the selected IFM institutions which are located in France.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cohort 1 | All consecutive patients with complete set of data (and who underwent apheresis) treated between 2009 and 2013 with G-CSF and plerixafor | ||
| Cohort 2 | All consecutive patients with complete data (and who underwent apheresis) treated between 2009 and 2013 with G-CSF and cyclophosphamide |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Total cost of stem cell mobilization procedure (including remobilisation if applicable) | 2009-2013 |
| Measure | Description | Time Frame |
|---|---|---|
| Number of visits for administration of mobilizing agents | 2009-2013 | |
| Duration (days) of administration of mobilizing agents | 2009-2013 | |
| Agents used as mobilizing agents |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
The first group of patients will have received plerixafor plus G-CSF without the administration of chemotherapy as a mobilization strategy and a second group of patients will have received cyclophosphamide plus G-CSF as a mobilization strategy.
All consecutive patients with complete set of data (and who underwent apheresis) treated between 2009 and 2013 with G-CSF and plerixafor and all consecutive patients with complete data (and who underwent apheresis) treated between 2009 and 2013 with G-CSF and cyclophosphamide will be included.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Xavier Leleu, Dr | Service des maladies du sang, Hôpital Huriez, CHRU, Lille | Study Chair |
| Denis Caillot, Dr | Service d'Hématologie Clinique, Hôpital Le Bocage, CHU Dijon | Study Director |
| Eric Deconinck, Pr | Hématologie, Hôpital Jean Minjoz, CHU Besançon | Study Director |
| Samuel Limat, Pr | Pharmacie centrale, Hôpital Jean Minjoz, CHU Besançon | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU Dijon | Dijon | 21000 | France | |||
| Centre Hospitalier Universitaire (CHU) de Limoges |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009101 | Multiple Myeloma |
| ID | Term |
|---|---|
| D054219 | Neoplasms, Plasma Cell |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D020141 | Hemostatic Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
| 2009-2013 |
| Attainment of CD34+ target (yes, no) (min 2.106 cells/kg, ideal >4.106cells/kg) | 2009-2013 |
| Number of days needed to meet CD34+ target level (min 2.106 cells/kg, ideal >4.106cells/kg) | 2009-2013 |
| Limoges |
| 87042 |
| France |
| Centre Hospitalier Lyon Sud | Lyon | 69495 | France |
| CHRU Hôtel Dieu | Nantes | 44035 | France |
| Institut Curie Centre de Lutte Contre le Cancer (CLCC) | Paris | 75005 | France |
| La Pitié Salpetriêre | Paris | 75013 | France |
| Hôpital Saint-Antoine | Paris | 75571 | France |
| Hôpital Robert Debré Hématologie | Reims | 51092 | France |
| Centre Henri Becquerel | Rouen | 76038 | France |
| D014652 |
| Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010265 | Paraproteinemias |
| D001796 | Blood Protein Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006474 | Hemorrhagic Disorders |
| D008232 | Lymphoproliferative Disorders |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |